All news from Anaesthesiology

A Novel Treatment Target for Idiopathic Pulmonary Fibrosis Discovered

A group of scientists at the Cincinnati Children's Hospital Medical Center has found a new molecular target that slows or stops the deadly and mostly untreatable lung disease, idiopathic pulmonary fibrosis (IPF).

The study, published in the journal Cell Reports, demonstrated that a gene called FOXF1 inhibits the IPF disease process, which includes extensive scarring in lung connective tissues, hyperproduction of myofibroblasts and excessive lung inflammation.

Circadian Clock May Control Daily Rhythms of Aggression

In a study published in Nature Neuroscience, a team of American scientists at Beth Israel Deaconess Medical Center (BIDMC) has demonstrated the circadian clocks may regulate the aggressive behaviors of male mice, opening the door to potential opportunities for managing the evening-time agitation common in patients with degenerative neurological disorders.

Swine Acute Diarrhea Syndrome Coronavirus and Mortality Risks

A newly identified coronavirus that killed nearly 25,000 piglets in 2016-17 in China emerged from horseshoe bats near the origin of the severe acute respiratory syndrome coronavirus (SARS-CoV), which emerged in 2002 in the same bat species.

The new virus, called swine acute diarrhea syndrome coronavirus (SADS-CoV), does not appear to infect people, unlike SARS-CoV. The research is published in the journal Nature.

Physical Exercise May Influence The Health of Future Offspring

Resaerchers from German Center for Neurodegenerative Diseases (DZNE) examines whether physical and mental exercise can influence the health of future offspring. The study, published in Cell Reports, suggests that physical and mental exercise is not only beneficial for your own brain, but can also affect the cognitive ability of future offspring – at least in mice.

Inactivation Of A Protein In Fat Cells

Researchers recently discovered that inactivation of a protein called p62 in fat cells fuels aggressive, metastatic prostate cancer in mice. The findings suggest that mTOR inhibitors currently used to treat a wide range of cancers may have the unintended consequence of shutting down fat tissue metabolism and fueling tumor growth. The study was published in Cancer Cell.

Role of Neuraminidase in H1N1

Vaccines designed to protect people from the influenza virus tend to concentrate on hemagglutinin, one of the two prominently displayed proteins on the surface of the virus and the primary target for influenza prevention.