Denosumab is more efficacious than the risedronate in boosting bone mineral density (BMD) at the lumbar spine in patients newly initiating or continuing glucocorticoids who are at risk of fractures, according to findings from a global, randomized, active-controlled trial.
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There are no clinical and survival benefits of adding selective internal radiation therapy (SIRT) to standard sorafenib treatment in patients with unresectable, locally advanced primary liver cancer, when compared with using sorafenib alone, according to the SORAMIC study presented at The International Liver Congress™ 2018 in Paris, France.
A novel 6D cardiac magnetic resonance (CMR) imaging that is unaffected by cardiac or respiratory motion, and in fact captures such motion as part of the imaging process, could potentially sharpen and simplify CMR procedures, according to a study published in Nature Biomedical Engineering.
An extremely powerful and versatile mouse model of cancer, developed by the researchers from the Seve Ballesteros Foundation-CNIO Brain Tumour Group at the Spanish National Cancer Research Centre (CNIO), will improve cancer research and accelerate pre-clinical testing of novel targeted therapies, a new study published in Nature Communications reports.
Researchers from the University of Iowa have identified a new population of lung stem cell that repairs the organ's gas exchange compartment following severe injury. The cells, known as glandular myoepithelial cells (MECs), were found to be surprisingly flexible. The study, published in Cell Stem Cell, shows that MECs can self-renew and differentiate into seven distinct cell types in the airway, making them the most plastic lung stem cell.
A new study from the University of Toronto reveals that specific parts of the hippocampus–an area of the brain commonly linked with memory and dementia–may yield important clues to a range of mental health issues such as anxiety, addiction, and depression.
Some patients with POCD experience memory problems; others have difficulty multitasking, learning new things, following multistep procedures or setting priorities. Unlike delirium, an acute, sudden-onset disorder that affects consciousness and attention POCD can involve subtle, difficult-to-recognize symptoms that develop days to weeks after surgery. Most of the time, POCD is transient and patients get better in several months. The study was published in the New England Journal of Medicine.
A novel nutraceutical called nicotinomide riboside has been found to kick-start the same biological pathways as calorie restriction does, and boost arterial health in people with mild hypertension.
The American College of Cardiology (ACC) and American Heart Association (AHA) have released a new set of performance and quality measures for cardiac rehabilitation (CR).
Scientists used an experimental targeted molecular therapy to block a matrix-forming protein in heart cells damaged by heart attack, reducing levels of scarred muscle tissue and saving mouse models from heart failure.
A Children's-led research team has turned the tables on Schistosoma haematobium, a parasitic worm that freeloads in humans, by using a protein derived from the parasite as a therapeutic molecule to reduce bleeding and pain associated with chemotherapy-induced hemorrhagic cystitis.
Investing in the continuity of care for lung cancer patients can bring tremendous benefits in terms of patient satisfaction and quality of life. In Quebec, Canada, this investment has taken the form of a dedicated role on the medical team: The Pivot Nurse in Oncology (PNO). A study presented at ELCC 2018 (European Lung Cancer Congress) in Geneva has produced new evidence of the different ways in which this service improves patients' lives during treatment.