Individual cells take on their identities by switching on distinct sets of genes, producing different sets of RNA and protein molecules. Thousands of distinct cell types are needed to build a fully developed newborn. So far, the overall rate of protein synthesis has been regarded as a "housekeeping" activity that does not play a major role in defining cell types.
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A new study shows that transplant biopsy system that uses gene chips to read molecules is far safer and more effective than existing approaches used for heart transplant biopsies and is showing promising results for lung transplant biopsies. An international team of transplant specialists–including Philip Halloran, the founder of the "molecular microscope" system–presented early clinical trial findings of the system today at the 2018 meeting of the International Society for Heart and Lung Transplantation in Nice, France.
Researchers from the University, they showed that stable joint cartilage could be produced from adult stem cells originating from bone marrow. This is made possible by inducing specific molecular processes occurring during embryonic cartilage formation. The study was published in the scientific journal PNAS.
A study was to develop a written examination to assess general aviation (GA) pilots’ understanding of aviation meteorology products. When tested on their knowledge of 23 types of weather information, from icing forecasts and turbulence reports to radar, 204 general aviation (GA) pilots surveyed by Embry-Riddle Aeronautical University researchers were stumped by about 42% of the questions. The study was published in the International Journal of Aerospace Psychology.
According to a study, researchers assessed that antibiotics have greatly reduced the dangers of ear infections serious neurological complications, including hearing loss, facial paralysis, meningitis and brain abscess still occur. The study was published in the journal Current Neurology and Neuroscience Reports.
Scientists used an experimental targeted molecular therapy to block a matrix-forming protein in heart cells damaged by heart attack, reducing levels of scarred muscle tissue and saving mouse models from heart failure. Researchers are testing a manufactured peptide called pUR4 to block the fibronectin protein in human heart cells donated by heart failure patients. The study was published in the journal Circulation.
Researchers demonstrated against the high cost of insulin in the United States held in the capital this past weekend. Physicians joined patients with diabetes and other activists protest, it was held on April 8, was organized by the Right Care Alliance, a grassroots activist group of clinicians, patients, and other stakeholders dedicated to making "health care institutions accountable to communities and put patients, not profits, at the heart of health care."
According to study, researchers have identified a novel therapeutic vulnerability in NRAS mutant melanoma and an effective strategy to address it, using a combination of two clinically relevant inhibitors.NRAS mutant melanoma represents about 25% of melanoma cases. The prognosis for patients is poor because NRAS mutant melanoma is aggressive and resistant to most therapies. Also, development of secondary NRAS mutations represents a mechanism of acquired resistance to targeted therapies. The study was published online in EMBO Molecular Medicine.
Researchers team with bioengineering students created an add-on for automated external defibrillators aka AEDs that literally punches through the skin to help deliver a jolt to a person in cardiac arrest. The skin presents a formidable barrier to life-saving defibrillators, but a team of students from Rice University believes it has found a way around that problem. The students developed a needle-laden pad that can be pressed through both a flexible AED pad and the skin to overcome the skin's typical impedance of around 500-kiloohms per square centimeter.
A new study showing that researchers examine a single foodborne outbreak could cost a restaurant millions of dollars in lost revenue, fines, lawsuits, legal fees, insurance premium increases, inspection costs and staff retraining. It was based on computer simulations that suggest a foodborne illness outbreak can have large, reverberating consequences regardless of the size of the restaurant and outbreak. The study was published online in the journal Public Health Reports,
According to the research, scientists assessed the risk of acute kidney injury (AKI) and mortality associated with intensive systolic blood pressure reduction in acute intracerebral hemorrhage (ICH)
The present study suggests that outcome of patients with fever of unknown origin (FUO) whose 18F-FDG PET/CT finding is non-diagnostic would be favorable