All news from Anaesthesiology

A Transplant Biopsy Is Safer And More Effective By 'Molecular Microscope'

A new study shows that transplant biopsy system that uses gene chips to read molecules is far safer and more effective than existing approaches used for heart transplant biopsies and is showing promising results for lung transplant biopsies. An international team of transplant specialists–including Philip Halloran, the founder of the "molecular microscope" system–presented early clinical trial findings of the system today at the 2018 meeting of the International Society for Heart and Lung Transplantation in Nice, France.

Assessing General Aviation Pilots Understanding of Aviation Weather Products

A study was to develop a written examination to assess general aviation (GA) pilots’ understanding of aviation meteorology products. When tested on their knowledge of 23 types of weather information, from icing forecasts and turbulence reports to radar, 204 general aviation (GA) pilots surveyed by Embry-Riddle Aeronautical University researchers were stumped by about 42% of the questions. The study was published in the International Journal of Aerospace Psychology.

Inhibiting Fibronectin Might Prevent Heart Failure

Scientists used an experimental targeted molecular therapy to block a matrix-forming protein in heart cells damaged by heart attack, reducing levels of scarred muscle tissue and saving mouse models from heart failure. Researchers are testing a manufactured peptide called pUR4 to block the fibronectin protein in human heart cells donated by heart failure patients. The study was published in the journal Circulation.

Patients With Diabetes Protesting Insulin Prices

Researchers demonstrated against the high cost of insulin in the United States held in the capital this past weekend. Physicians joined patients with diabetes and other activists protest, it was held on April 8, was organized by the Right Care Alliance, a grassroots activist group of clinicians, patients, and other stakeholders dedicated to making "health care institutions accountable to communities and put patients, not profits, at the heart of health care."

A New Therapy Effective For NRAS Mutant Melanoma

According to study, researchers have identified a novel therapeutic vulnerability in NRAS mutant melanoma and an effective strategy to address it, using a combination of two clinically relevant inhibitors.NRAS mutant melanoma represents about 25% of melanoma cases. The prognosis for patients is poor because NRAS mutant melanoma is aggressive and resistant to most therapies. Also, development of secondary NRAS mutations represents a mechanism of acquired resistance to targeted therapies. The study was published online in EMBO Molecular Medicine.

Biologists Develop Add-On Pad To make Defibrillators More Effective

Researchers team with bioengineering students created an add-on for automated external defibrillators aka AEDs that literally punches through the skin to help deliver a jolt to a person in cardiac arrest. The skin presents a formidable barrier to life-saving defibrillators, but a team of students from Rice University believes it has found a way around that problem. The students developed a needle-laden pad that can be pressed through both a flexible AED pad and the skin to overcome the skin's typical impedance of around 500-kiloohms per square centimeter.

Single foodborne outbreak can have large ramifications for restaurants

A new study showing that researchers examine a single foodborne outbreak could cost a restaurant millions of dollars in lost revenue, fines, lawsuits, legal fees, insurance premium increases, inspection costs and staff retraining. It was based on computer simulations that suggest a foodborne illness outbreak can have large, reverberating consequences regardless of the size of the restaurant and outbreak. The study was published online in the journal Public Health Reports,