Researchers reported that Allopurinol-associated cutaneous adverse reactions severe enough to require hospitalization occurred three to six times as often in Asians, blacks, and Native Hawaiians/Pacific Islanders than in whites or Hispanics, and up to 12 times as often in members of the high-risk groups who were also female and older than 60 years
No differences found in hospitalized infections or effectiveness in patients with rheumatoid arthritis (RA) who previously received treatment with methotrexate and who initiated treatment with tofacitinib or non-TNF biologics, a new study published in Arthritis Research & Therapy reports.
Researchers from the University of Colorado Cancer Center challenges the use of whole-brain radiation for brain metastases from small-cell lung cancer (SCLC). The study, published in the journal Lung Cancer, found that median overall survival was longer for SCLC patients who received whole-brain radiation therapy, when compared with patients who received stereotactic radiosurgery (SRS).
In high-level Olympic athletes, many spinal diseases arise from overuse, while others are the result of acute injury. A new study, published in BMJ Open Sport & Exercise Medicine analyze the various pathologies that affect the spine in high-level athletes by evaluating the MRIs of the spine in athletes who participated in the 2016 Rio Summer Olympics.
A new clinical trial, reported in the Cancer Discovery, reveals that an experimental drug is effective and safe for patients with cancers caused by an alteration in the receptor tyrosine kinase (RET). The drug seems to be promising as a potential therapy for RET-driven cancers, such as medullary and papillary thyroid, non-small cell lung, colorectal and bile duct cancers.
A new study published in the journal Arthritis Research and Therapy reveals that the presence of antibodies against the chemokine receptors CXR3 and CXR4 linked with the severity of interstitial lung disease related to systemic sclerosis.
Early life stress leaves the persistent molecular trace in the brain and affects sleep. Also, early life onset depression is associated with the severity of the depressive symptoms, new doctoral study reports.
Researchers at NeuRA in collaboration with scientists in Melbourne investigated why people with paralysis of their limbs and torso are more likely to suffer from sleep apnea. The findings, reported in the The Journal of Physiology, could be used to develop much-need targeted therapies.
People with chronic back pain often try painkillers and other treatments without success. A new study, published in JAMA Neurology, suggests a program of education and exercise may provide relief for patients with chronic back pain.
Anti-PD-1 therapy provided for early-stage lung cancer patients before they undergo surgery showed major tumor responses in the removed tumor and an increase in anti-tumor T-cells that remained after the tumor was removed, which resulted in fewer relapse cases in the patients, a new study published in the New England Journal of Medicine reports.
A drug given to early stage lung cancer patients before they undergo surgery showed major tumor responses in the removed tumor and an increase in anti-tumor T-cells that remained after the tumor was removed, which resulted in fewer relapse cases in the patients.
A new study published in the journal PNAS found that malaria-infected individuals are more attractive to mosquitoes because they emit specific odors from their skin could yield new biomarkers of the disease and better insect traps.