All news from Anaesthesiology

MRI Shows Brain's Lining Heal After a Concussion

Scientists from the National Institutes of Health (NIH) have observed in real time how immune cells fix damaged lining of the brain, or meninges, after a concussion.

Researchers watched the process in the brains of mice in real-time via MRI, which may help provide further knowledge regarding how humans heal after experiencing a concussion or mild traumatic brain injury (mTBI), according to a m study published in the journal Nature Immunology.

Lupus Treatment Shows Positive Results in Phase III Clinical Trial

A new study, published in the journal Arthritis & Rheumatology, describe positive late stage study results for an investigational lupus therapy. The study indicates that belimumab, a monoclonal antibody therapy that targets a component of the immune system, provides considerable benefits to patients with systemic lupus erythematosus (SLE), a predominately female, chronic inflammatory disease that can affect virtually any organ.

Study Examines How Higher-order Gene Combinations Help Maintain Normal Cell Physiology

The researchers at the University of Minnesota and the University of Toronto examines for the first time how higher-order gene combinations–-comprising three genes–-help maintain normal cell physiology. The findings, reported in the journal American Association for the Advancement of Science (AAAS), could help develop new life-saving treatments to combat diseases such as cancer, heart disease, and diabetes.

Ivermectin Ineffective Against Pediatric Trichuriasis

A new study, published in the journal Clinical Infectious Disease, suggests that ivermectin can be administered safely to preschool- and school-aged children suffering from trichuriasis– infection caused by the parasitic worm Trichuris trichiura.

But the use of ivermectin to treat trichuriasis is ineffective at 200-µg/kg doses in preschool- and school-aged children, with less efficacy observed in school-aged children when 600-µg/kg doses were administered to school-aged children.