All news from Anaesthesiology

To Prevent Cancer, Protein Goes Against the NF-?B Family

Researchers have made the surprise discovery that the 'odd one out' in a family of proteins known to drive cancer development is instead critical for preventing stomach cancers.  The research team showed switching off a gene called NF-κB1 caused the spontaneous development of stomach cancers, driven by chronic inflammation. The study also revealed that immunotherapy may prove to be a significant tool for treating stomach cancers that are driven by runaway inflammation, warranting further investigation. The study was published in the journal Immunity.

A Cell Therapy Aids Recovery Of Heart Without Implanting Cells

The adult human heart cannot regenerate itself after injury, and the death of cardiac muscle cells, known as cardiomyocytes, irreversibly weakens the heart and limits its ability to pump blood. Heart disease is a major global health problem, myocardial infarction annually affects more than one million people in the U.S. alone, and there is still no effective treatment. The study was published in Nature Biomedical Engineering.

Super-Resolution Microscopy Visualizes All The Strands Of A DNA

A study examines that researchers have used a new variant of super-resolution microscopy to visualize all the strands of a DNA-based nanostructure for the first time. The method promises to optimize the design of such structures for specific applications. The term 'DNA origami' refers to a method for the design and self-assembly of complex molecular structures with nanometer precision.The study was published in the journaNature Communications.

Low Testosterone Levels in Men Leads To Chronic Disease

A study found that low amounts of the hormone could also be associated with chronic disease, even among men 40 years of age and younger. A male's total testosterone level may be linked to more than just sexual health and mass muscle preservation. By looking at data for men from a population level, it has become evident over time that chronic disease is on the rise in older males," says Mark Peterson. The study was published in Scientific Reports. They studied this relationship among testosterone, age and chronic disease.

Suspicion For Acute Aortic Dissection Should Be Raised When Patients Have High Specificity

A study estimates that an appropriate clinical setting, suspicion for acute aortic dissection should be raised when patients present with findings that have high specificity and high positive likelihood ratio (hypotension, pulse deficit, or neurologic deficit). The study was published in the Journal of Academic Emergency Medicine. Acute aortic dissection is a life?threatening condition due to a tear in the aortic wall. It is difficult to diagnose and if missed carries a significant mortality.