According to a study, researchers have created a new technique to hunt for hormones that influence how organs and tissues communicate with each other. The method enabled them to find naturally occurring molecules that play major roles in Type 2 diabetes, obesity and cardiovascular disease. The study was published in Cell Metabolism.
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A new research discovered drugs that induce a self-inflicted cell-death process called ferroptosis could be used to target de-differentiated melanoma cells, thereby increasing the efficacy of both targeted and immune therapies. Ferroptosis is much more recently discovered and fundamentally different from apoptosis. Ferroptosis is mechanistically founded on the insufficient anti-oxidant protection of cellular lipid membranes, whereas the death pathway of apoptosis is mechanistically linked to the mitochondria of the cell.
According to a new study, research examining patients who received home care visits from nurses were more likely to visit the emergency department during the evening on the same day, particularly for non-urgent issues. An emergency department visit is not necessarily a negative outcome, but may be if a frail patient could more appropriately be treated by their usual community-based providers who know them best.
A new study estimates that in 2014 Ebola outbreak in West Africa killed more than 11,000 people and was the deadliest outbreak since the discovery of the virus in 1976. It is linked to start of the outbreak to a two-year-old in Meliandou, a remote village in Guinea, a country that had never before seen a case of Ebola. The type of virus was identified as the deadliest strain, found in Zaire, a country thousands of miles away. The study was published in New England Journal of Medicine study.
The present study demonstrated the most robust 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) changes in the left posterior cingulate cortex (PCC)/precuneus in amnestic mild cognitive impairment (aMCI) converters relative to aMCI non-converters at baseline
In the study, researchers discussed novel treatment options for rheumatoid arthritis (RA), including biosimilars, that are available, as well as to highlight promising agents in development and also to discuss new emerging safety signals associated with these drugs and to discuss strategies in tapering therapy
According to new research, synthetic opioids have surpassed prescription opioids as the most common drug class involved in overdose deaths in the United States, especially when combined with other prescription or illicit drugs
According to a new study from researchers at Magee-Womens Research Institute (MWRI), increased prevalence of hepatitis C virus (HCV)-exposed infants are not adequately screened and many pediatric HCV infections remain undetected
According to the findings, the study could lead to new ways to eliminate antibiotics from land and water, the researchers said. Environmental antibiotic contamination promotes drug resistance and undermines our ability to treat bacterial infections
In the study, sonication prosthetic fluid PCR was found to have adequate and clinically acceptable diagnostic values for detecting Periprosthetic joint infection (PJI), with a sensitivity of 75% and specificity of 96%
According to the study, researchers have developed a contact lens that may help people with colour blindness simply by using a low cost dye
Long-acting reversible contraceptives (LARC) are suitable for use by adolescents, according to a Committee Opinion published in the May issue of Obstetrics & Gynecology