All news from Anaesthesiology

Immunotherapy Treatments Could Survive Eye Inflammation Patients

An Eye inflammation and uveal effusion develop among patients taking anti-cancer immune checkpoint inhibitor therapy. New immunotherapy treatments offer a remarkable chance for survival for patients with advanced melanoma and hard-to-treat cancers of the bladder, kidney, and lung. Patients receiving immune checkpoint inhibitors developed uveal effusions and eye inflammation that affected their vision. The study was published in JAMA Ophthalmology

Severe Allergic Reactions Caused By Poison Ivy And Poison Oak

A study determined that the arrival of troublesome plants such as poison ivy and poison oak that can cause mild to severe allergic reactions. The signature leaves of three of the poison ivy plant carry an oil called urushiol that can be an irritant if touched, broken or burned. Poison ivy's less-common cousin, poison oak, can be identified by leaves that look like hairy oak fronds. While some people are not sensitive to the urushiol oil, others develop a red, itchy or painful rash, swelling or blisters where the irritant comes in contact with the skin.

Breast Cancer Associated With The Body's Circadian Rythm

A study estimated a new gene, which may have an impact on breast cancer associated with the body's circadian rhythm. In the past, doctors have associated the BRCA1 and BRCA2 gene mutations with an increased risk of breast cancer. They add to a growing list that ties disruptions to our circadian rhythm that is, the "central clock" mechanism in our brains to a higher risk of cancer progression, obesity, some neuromuscular diseases, and other impairments, including jet lag. The study was published in the journal Development,

Genetic Variations Could Increase The Risk Of Heart Attack

According to a new study, the research team has discovered genetic variations that increase the risk of heart attack even when patients are receiving a statin drug like Lipitor or Crestor to lower their blood cholesterol. They help some patients experience a heart attack or the need for coronary revascularization to open blocked heart arteries while taking statins. It suggests that drugs targeting the genetic variations could lower the heart risk in these patients. The study was published in the journal Circulation.

Identifying Potential Lead Compounds By HT-ADME

Researchers announced that Charles River Laboratories International recently announced the expansion of its service capabilities in early discovery screening. Charles River is the first contract research organization to offer clients access to Apricot Designs' Dual Arm (ADDA) system for high-throughput absorption, distribution, metabolism, and excretion (HT-ADME) to identify potential lead compounds in North America and Europe.

Gut Bacteria Helps For Immune Responses

Researchers have shown that it is possible to favor the engraftment of one gut bacterial strain over others by manipulating the mice's diet. The researchers also have shown it's possible to control how much a bacterium grows in the intestine by calibrating the amount of a specific carbohydrate in each mouse's water or food. Gut bacteria thrive on the food we eat.

In turn, they provide essential nutrients that keep us healthy, repel pathogens and even help guide our immune responses. The study was published in Nature. By Understanding some bacterial strains, they can ingest successfully take up residence in the large intestine, while others are quickly evicted, could help scientists learn how to manipulate the makeup of thousands of bacterial species there in ways that enhance our health. But the sheer complexity of gut ecology has hampered this task.

Patients With Chronic Sciatica Have Inflammation In Nervous System

A study conducted on patients having inflammation in the areas of the nervous system. Location of inflammation may determine which patients are successfully treated with steroid injections. Investigators have found, for the first time in humans, that patients with chronic sciatica, back pain that shoots down the leg have evidence of inflammation in key areas of the nervous system. The study was published in the journal Pain.

Bisexual Women And Lesbian Develop Type 2 Diabetes Due To Stress

Researchers found that lesbian and bisexual women participating in a major longitudinal study have a greater incidence of type 2 diabetes than heterosexual participants, and higher BMI explained this association. In a newly published study involving 94,250 women across the United States, researchers found that lesbian and bisexual (LB) women were more likely than heterosexual women to develop type 2 diabetes during the course of the 24-year study follow up.

They investigated the incidence of type 2 diabetes in lesbian and bisexual women and heterosexual women in a large, longitudinal U.S. cohort. The study was published in Diabetes Care. For the study, the team analyzed survey results dating back to 1989 from women participating in the Nurses' Health Study II, which is one of the largest investigations into the risk factors for major chronic diseases in women.

Emergency Medicines To Fight Against Their Opioid Epidemic

Asking emergency department (ED) providers to self-identify their opioid prescribing practices and then providing them with timely, clinically relevant, individualized, and actionable feedback on their actual opioid prescribing data, significantly decreases future opioid prescribing among providers who underestimate their baseline prescribing. The study was published in the journal Academic Emergency Medicine (AEM).