All news from Anaesthesiology

Patients With Type 2 Diabetes And Obesity Is Controlled

A study developed a medical device company that is developing EndoBarrier®for patients with type 2 diabetes and obesity, is pleased to announce the meta-analysis, "Effects of the Duodenal-Jejunal Bypass Liner on Glycemic Control in Type 2 Diabetic Patients with Obesity: A Meta-analysis with Secondary Analysis on Weight Loss and Hormonal Changes. The study was published in the journal Diabetes Care.

Drug-Resistant Melanoma Developed Resistance To A Targeted Therapy

Researchers have now exposed this acquired vulnerability in melanoma that has developed resistance to a targeted therapy with BRAF inhibitors. The team then developed a new therapeutic strategy to selectively kill the drug-resistant cancer cells. Cancer cells that develop resistance to drugs pay a price for this by simultaneously developing a new vulnerability. If this acquired vulnerability can be identified, it may be exploited clinically.

A High-Quality CPR Is Used In Emergency Department

Researchers are trained in high-quality CPR for more than three decades, including the past 16 years in the emergency department of the University of Alabama at Birmingham Hospital. For Lovelace, teaching CPR meant knowing his words could potentially save a life. He never imagined that life would be his own. But when Lovelace had a massive heart attack that triggered a cardiac arrest last April while at work, it was the training he provided his colleagues, who jumped in and performed CPR, that kept him alive.

Intentions Predicted to Help Depressed In Sri Lanka

Studies have found that although there are high rates of depression among university students, their help-seeking practices are poor. It is important to identify students who are less likely to seek the necessary help, to encourage better help-seeking among them.

This study, which was conducted among undergraduates in Sri Lanka, examined the associations between personal characteristics of the undergraduates and their intentions to seek help for depression.

CRISPR-Cas9 technology: Prediction of Cancer Mutational Signatures

Mutations driving cancer development leave behind specific 'scars,' so-called mutational signatures, in the genome. In principle, they allow for profiling of the cancer type and its development — but the noisy environment of a cancer genome makes correlations difficult. Using CRISPR-Cas9 technology, researchers were able to show for the first time that specific genetic alterations indeed lead to the predicted mutational signatures observed in human cancers.

Rise in Mercury Levels with Continuous Consumption of Pangasius

The pangasius, originally from Vietnam, is one of the most popular fish in the world due to its low cost, mild flavor and fillet presentation without skin or bones. It is specially requested in school canteens and senior centers. But a toxicological evaluation carried out by a team of Spanish scientists now shows that the mercury content in some samples exceeds all limits, so the consumption of other fish in the child population is recommended.

Combination Therapy Effective Against Aggressive Form of Thyroid Cancer

The U.S. Food and Drug Administration approved Tafinlar (dabrafenib) and Mekinist (trametinib), administered together, for the treatment of anaplastic thyroid cancer (ATC) that cannot be removed by surgery or has spread to other parts of the body (metastatic), and has a type of abnormal gene, BRAF V600E (BRAF V600E mutation-positive).