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Blood Donations for Zika, Screening is costly

Screening blood donations for Zika virus (ZIKV) in the United States is costly with low yield, according to a study published in New England Journal of Medicine. Researchers implemented investigational screening of donated blood for ZIKV RNA with transcription-mediated amplification (TMA).

Repeat TMA, TMA testing in exploratory mini pools, real-time reverse-transcriptase polymerase chain reaction, immunoglobulin M (IgM) serologic testing, and red-cell TMA were performed as confirmatory testing of reactive donations.

New Strategy To Tolerate the Infection Without Eliminating Pathogen

The prospective study has recently been challenged as scientists have taken a lesson from plant biologists about an ancient strategy involving the ability to "tolerate" rather than "resist" infection to maintain health. This concept referred to as "disease tolerance", provides an opportunity to develop new strategies that mitigate the consequences of infection