All news from Paediatrics

CHOP Celebrates EC Approval of Only Gene Therapy for Patients with Inherited Retinal Disease

Children's Hospital of Philadelphia (CHOP) celebrates a pivotal moment in medicine: approval by the European Commission (EC) of LUXTURNA® (voretigene neparvovec), the first and only gene therapy for patients with an inherited retinal disease, last month. This also makes LUXTURNA the first gene therapy for a genetic disease that has received regulatory approval in both the U.S. and European Union (EU)

New PET Tracer Identified For Imaging Tau in Alzheimer's Disease Patients

In the diagnosis of Alzheimer's disease and the search for effective treatments, tau tangles in the brain have joined amyloid build-up as markers of the disease and potential therapeutic targets. In the December issue of The Journal of Nuclear Medicine, the featured article of the monthly reports on the identification of a promising second-generation positron emission tomography (PET) tracer for imaging and measuring tau pathology

Adding New Channels to The Brain Remote Control

Now one of the pioneers of 'optogenetics' and colleagues have created two new tools—protein pores which when illuminated allow Ca2+ into cells or K+ out—for switching neurons on or off using light. Published in Frontiers in Neuroscience, their study shows that these synthetic 'ion channels' can be used to control specific neurons, even in live animals

A New Therapeutic Target for Metastatic and Resistant Prostate Cancers

Prostate Cancer researchers from the Bellvitge Biomedical Research Institute (IDIBELL), led by Dr. Álvaro Aytés report a new combined therapy to fight the most aggressive and resistant prostate cancers. The team, which has just published its results in Nature Communications, also includes researchers from the Catalan Institute of Oncology, Columbia University in New York and the University of Bern in Switzerland

Five Ways to Reduce the Risk of Stillbirth

Stillbirth is defined as the death of a baby of at least 20 weeks' gestation or 400 grams in weight. Most stillbirths occur during pregnancy. There's been a reduction over the past 20 years of baby deaths within the first four weeks of life. But stillbirth rates have not declined. The current rate of 7.1 per 1,000 births puts Australia 28th among the 34 OECD countries for stillbirth