All news from Medical Toxicology

Mycobacterium Chimaera Infections, An Ongoing Global Outbreak

An ongoing global outbreak of Mycobacterium chimaera infections is associated with contamination of a widely used surgical device, the 3T heater-cooler unit, researchers report. The outbreak began in Switzerland in 2011, and since then the Swiss Chimaera Taskforce estimates an annual incidence of 156-282 cases for the Ten major valve replacement markets, with 51-80 cases in the U.S. alone.

In Toxoplasma gondii, Protein Targets of Thiazolidinone Derivatives Elaborated

Thiazolidinone derivatives show inhibitory activity (IC50) against the Toxoplasma gondii parasite, as well as high selectivity with high therapeutic index . To disclose the target proteins of the thiazolidinone core in this parasite, researchers explored in silico the active sites of different T. gondii proteins.

Researchers estimated thiazolidinone molecules with an inhibitory effect on invasion and replication of the parasite inside host cells. This enabled us to describe some of the most suitable structural characteristics to design a compound derived from the thiazolidinone core

Simulation-Based Training of Emergency Medical Providers In USA

Training emergency medical services (EMS) workforce is challenging in rural and remote settings. Moreover, critical access hospitals (CAHs) struggle to ensure continuing medical education for their emergency department (ED) staff. This project collected information from EMS and ED providers across Nebraska to identify gaps in their skills, knowledge, and abilities and thus inform curriculum development for the mobile simulation-based training program.

Pediatric Medicolegal Autopsy in France: A Forensic Histopathological Approach

The aim of postmortem medicolegal examination in pediatric death is primarily to establish the circumstances and causes of death and to exclude child abuse. In France, pediatric death is systematically documented by medicolegal or medical autopsy. In the case of a medicolegal autopsy, the complementary examinations, requested and financed by justice, are rarely limited to a histopathological examination.