All news from Anaesthesiology

Effectiveness of SHP2 Inhibitors Against Hard-to-Treat Cancers

A new anti-cancer drug may be effective against a wider range of cancers than previously thought. Using a mouse model and samples taken from cancer patients researchers has shown that a new class of drugs known as SHP2 inhibitors is also effective against aggressive, hard-to-treat tumors such as lung and pancreatic cancers. Clinical trials currently underway had previously excluded patients with these cancers.

Key Challenge of R&D Efficiency Examined

ICON plc, a global provider of drug development solutions and services to the pharmaceutical, biotechnology, and medical device industries, announced the results from a new survey of pharmaceutical executives and professionals by ICON and Pharma Intelligence, which examines the key challenge of declining research and development (R&D) efficiency.

Evidence-based Medical Opinion on Abusive Head Trauma Outlined

Abusive head trauma (AHT), a medical diagnosis of infants and young children who suffer from inflicted intracranial and associated spinal injuries, is often misrepresented in legal proceedings of child abuse, according to a consensus statement supported by nine pediatric and radiology international organizations published in Pediatric Radiology. The statement outlines consensus of evidence-based medical opinion on AHT to confirm the validity of the diagnosis and serve as a tool for the legal system.

Development of RIOCATH Urinary Catheter

The RIOCATH®(Reversal Inside-Out CATHeterisation) design greatly reduces the risk of introducing infection into the body as well as the trauma of sensitive tissues. So far, private investors have invested more than two million euros in the development. Clinical trials will begin by the end of this year and the first product market entry is expected in 2019.

Violence Against Women-Mitigation Policies in Sri Lanka

A systematic search for violence against women(VAW) legislation identified 124 countries/territories with some type of VAW legislation, of which only 28 mentioned the health sector. This is concerning as it is evident that women experiencing partner violence are more likely to make extensive use of health care services compared to non-abused women.

Novel Disease Mechanism in Chronic Smokers

Research published in the journal Clinical Science suggests that an immune signalling protein called interleukin (IL)-26 is increased among chronic smokers with lung disease and this involvement reveals disease mechanisms of interest for developing more effective therapy for these hard-to-treat patients.