All news from Anaesthesiology

TAVR: Holds Sway in Low-Risk Patients at 6 Years

Follow-up data from low-risk patients through 6 years of the NOTION trial continue to favor transcatheter aortic valve replacement (TAVR) with the self-expanding CoreValve (Medtronic) over surgical bioprostheses for valve hemodynamic performance and structural deterioration.

Microbiome Treatment For Atopic Dermatitis

According to a study, researchers examined that the treatment with Rmucosa was associated with significant decreases in measures of disease severity, topical steroid requirement, and Saureus burden. Topical treatment with live Roseomonas mucosaa bacterium naturally present on the skin was safe for adults and children with atopic dermatitis (eczema) and was associated with reduced disease severity. The study was published in JCI Insight.

Drug Discovery: Enhancement With Human-Relevant Research

The average pre-approval cost of research and development for a successful drug is estimated to be US$2.6 billion and the number of new drugs approved per billion US dollars spent has halved roughly every 9 years since 1950.

More than 90% of drug candidates entering clinical trials fail to gain regulatory approval, mainly as a result of insufficient efficacy and/or unacceptable toxicity, because of the limited predictive value of preclinical, animal-based studies. Without significant intervention, the pipeline responsible for new drug production is predicted to dry up completely within 50 years.

Avatar App Applications In Emergency Care

An avatar-based application (app) can teach patients to recognize symptoms of heart attack and call emergency, according to a study presented today at EuroHeartCare 2018, the European Society of Cardiology's annual nursing congress. Patients using the app were more likely to call an ambulance when they had symptoms and had fewer hospital admissions.