Flooding the peritoneal cavity with heated chemotherapy during surgical resection of a form of metastatic colorectal cancer (CRC) does not improve survival over surgery alone and may increase complication rates, a French trial demonstrates.
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People who are prescribed a combination pill to manage their high blood pressure are more likely to take their medicine as instructed and have better health outcomes than those who take the same medications prescribed as separate pills, according to a new study.
Researchers identified immunological markers in nasal secretions and tears is becoming essential in the study of allergic diseases. The collection procedure of nasal and ocular secretions directly influences the results, thus it is of paramount importance to validate and standardize the sampling process.
A protein in the cell nucleus already targeted therapeutically for several types of cancer has now been linked to an aggressive form of pediatric liver cancer called hepatoblastoma (HBL), suggests a new study.
New research suggests that improving the quality of the average American's diet could substantially reduce the costs associated with heart disease, diabetes, cancer and other major health problems.
For tendon tissue engineering, tenocyte-seeded scaffolds are a promising approach. Under conventional 2D culture, however, tenocytes show rapid senescence and phenotype loss. Researches hypothesized that phenotype loss could be counteracted by simulated microgravity conditions.
A new study recommends that Doctors who do not have palliative care training are more likely to recommend aggressive surgery for patients with life-limiting diseases. Researchers surveyed 102 surgeons, oncologists, intensivists, and palliative care doctors near Sacramento, California, asking how they would respond to four different surgical scenarios in patients with very advanced cancers.
Researchers determine that patients undergoing same-day surgery, low functional health literacy is associated with poorer postoperative recovery and lower health-related quality of life. Patients in today's health care system are expected to take part and to be engaged in their own care. Consequently, they have to be able to read and understand health instructions on how to manage their own recovery at home.
Researchers determine trauma spills the contents of our cell powerhouses, it can evoke a potentially deadly immune response much like a severe bacterial infection. The study was published in the Journal of Trauma and Acute Care Surgery,
Researchers found that CK1 is the priming kinase that 'switches on' a key control point which plays an important role in regulating our biological clock. They abide by an external time schedule to eat, sleep, and go to work, our body is similarly dictated by internal clocks. Known as circadian rhythms, these daily cycles keep us on a regular 24-hour day and are involved in numerous aspects of our well-being.
Researchers team used cryo-electron microscopy to elucidate the structure of the protein, which may generate leads for drug development. The human glutamine transporter ASCT2 is upregulated in several forms of cancer. It is also the docking platform for a wide range of pathogenic retroviruses. The study was published in Nature Structural & Molecular Biology.
According to a new study, researchers determined that treating severe skin conditions with UV light rather than creams, pills, and injections could save the NHS millions of pounds while improving patient outcomes. The study was published in British Journal of Dermatology.