Researchers identify specialties prescribing opioids to surgical patients who develop new persistent opioid use. Greater coordination is needed between surgeons and physicians about the prescription of pain-relieving opioid drugs following surgery to help identify patients who are at risk of becoming opioid addicts. New persistent opioid use is a common postoperative complication, with 6% of previously opioid-naïve patients continuing to fill opioid prescriptions 3–6 months after surgery.
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For patients who live in rural areas, driving to see a specialist in a large city or at a university hospital can be challenging, if not impossible. People with liver disease often require multiple visits to adjust medications related complications.
Researchers have now structurally characterized late stages in the assembly of the human small ribosomal subunit, yielding detailed insights into their maturation principles. Ribosomes are the cell's protein factories. The study was published in the journal Nature.
Largest study to date shows that disrupted body clock rhythms are associated with increased susceptibility to depression, bipolar disorder, and adverse wellbeing. Disruption to normal daily circadian rhythms is associated with a greater susceptibility to mood disorders such as severe depression and bipolar disorder over the life course. The study was published in The Lancet Psychiatry.
A study recommends that Frequent Emergency Department Users: A Statewide Comparison Before And After Affordable Care Act Implementation. The odds of being a frequent user of California's emergency departments dropped in the two years following the implementation of major provisions of the Affordable Care Act (ACA) in January 2014, according to a new study led by UC San Francisco. The study was published in Health Affairs.
Researchers suggest Robert Burns may have had bipolar disorder. The findings Mood disorder in the personal correspondence of Robert Burns: Testing a novel inter-disciplinary approach are published in the Journal of the Royal College of Physicians of Edinburgh.
Even in adult brains, new neurons are generated throughout a lifetime. Research group led by Goethe University describes plastic changes of adult-born neurons in the hippocampus, a critical region for learning: frequent nerve signals enlarge the spines on neuronal dendrites, which in turn enables contact with the existing neural network. The study was published in the scientific journal PNAS.
SMCHD1 is required for chromosome to adopt conformation that suppresses gene expression. A research team has identified the essential role of a structural protein in the silencing of the inactive X chromosome, a process that prevents both copies of the same gene from being expressed in female mammals, which carry two copies of the X chromosome. The study was published in the journal Cell.
A new study evaluated that Only a small proportion of patients with end-stage renal disease (ESRD) on maintenance hemodialysis receive hospice care at the end of life, and almost half of those who do receive it enter hospice care within 3 days of their death. The study was published in JAMA Internal Medicine,
Moreover, patients with ESRD admitted to hospice have higher hospitalization and intensive care unit admission rates in the last week of life compared with patients who do not receive hospice care. The analysis shows, however, that Medicare costs do not differ substantially between those who do and those who do not receive hospice.
According to a study, researchers determine that Depression in type-1 diabetes patients is associated with higher levels of the inflammatory protein galectin-3. These findings suggest that galectin-3 levels may be useful for diagnosis of depression or may be a new target for treating depression associated with type-1 diabetes, which could lead to better patient care. The study was published in Endocrine Connections.