Researchers used periodontal ligament (PDL)-derived stem cells to create a cell sheet, attached it to a titanium implant, and transplanted it into the mandibular bone of a dog, demonstrating the formation of a periodontal-like structure containing both cementum- and PDL-like tissue. The study, which shows the feasibility of combining a regenerative cell sheet with a titanium dental implant. The study was published in Tissue Engineering.
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Researchers suggest, the local anesthetic drug, liposomal bupivacaine, did not reduce in-hospital opioid prescriptions or opioid-related complications in patients who received the drug during total knee replacement surgery as part of a multimodal approach to managing postsurgical pain. The study was published in Anesthesiology, the peer-reviewed medical journal of the American Society of Anesthesiologists (ASA).
Long periods of waking can lead to cognitive impairment, and the need to sleep continues to build up. Sleep then refreshes the brain through alterations in molecular biochemistry. These changes impact neuronal plasticity and brain function, but the molecular underpinnings of "sleepiness" are not well understood. The study was published in Nature.
A study explored the role of sleep in cognitive function of patients with abnormal glucose tolerance. Diabetes is linked to cognitive impairment. Sleep plays a role in memory consolidation. People with diabetes and prediabetes who have lower sleep efficiency,a measure of how much time in bed is actually spent sleeping have poorer cognitive function than those with better sleep efficiency. The study published in the journal Acta Diabetologica.
Researchers consider the D-transposition of the great arteries. D-transposition of the great arteries (d-TGA) is the second most common cyanotic congenital heart disease (CHD) lesion, accounting for 3-5% of all CHD, with a prevalence of 3 per 10,000 live births in the United States. The study was published in Cardiovascular Innovations and Applications.
Amyloid positron-emission tomography (PET) improves the diagnosis and treatment of dementia in daily clinical practice, according to results from the ABIDE project
In a study of patients with chronic kidney disease (CKD), persistent substance use—especially of hard illicit drugs—was linked with higher risks of CKD progression and early death. The findings appear in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN)
Golimumab can induce drug-free remission in some patients with early peripheral spondyloarthritis (SpA), according to findings published online May 27 in Arthritis and Rheumatology
According to a report by the World Health Organization, since adequate treatments are still lacking for many patients with anxiety and depression, the scientists at the Max Planck Institute of Psychiatry hope their research will inform the development of new, more effective treatments
A team of ear, nose, and throat (ENT) specialists has demonstrated that eating honey after swallowing a button battery has the potential to reduce serious injuries in small children
Various image analysis techniques show sex-specific patterns of bone deterioration at the hip, suggesting that men and women should be assessed differently for hip fracture risk, researchers say
Under the increased pressure of glaucoma, scientists want to help the neurons in our eyes better protect themselves and get better help from their friends