All news from Anaesthesiology

Spider Silk Microcapsules: Novel Vaccine Delivery Directly to Immune Cells

In order to strengthen the efficacy of vaccines on the immune system – and in particular on T lymphocytes, specialized in the detection of cancer cells – researchers have developed spider silk microcapsules capable of delivering the vaccine directly to the heart of immune cells. This process, published in the journal Biomaterials, could also be applied to preventive vaccines to protect against infectious diseases, and constitutes an important step towards vaccines that are stable, easy to use, and resistant to the most extreme storage conditions.

Biological Role of Bacterial enzymes

Rare earth elements (REEs) are an indispensable component of the digital technologies that are now an integral part of our everyday life. Yet their biological role has been discovered only recently. A few years ago it became apparent that these metals are essential elements for methano- and methylotrophic bacteria.

One representative is the bacterium Methylacidiphilum fumariolicum SolV, which was found in a volcanic mudpot near Naples, Italy, and is known to be strictly dependent on REEs such as lanthanum and cerium for its growth.

Gender-Based Violence and Child Abuse are Linked, New Finding

"No study to date had analyzed whether the occurrence of gender-based violence and child maltreatment – considered by the WHO as important public health problems and a violation of human rights – would also occur spatially, that is, if they overlap in the same areas and if the characteristics of these city areas that explain the risk of both types of violence are the same", said Enrique Gracia, Professor of Social Psychology at the University of Valencia and lead author of the article.

Breathing After Spinal Cord Injury Restored

One of the most severe outcomes of spinal cord injury from car accidents, sports impacts, or other neck trauma, is losing the ability to control breathing, with patients often requiring artificial ventilation for the rest of their lives. Researchers recently tested a hydrogel that releases a nerve-protecting agent at the site of injury, restoring independent breathing in rat models.The work was published in the The Journal for Neuroscience.

Affirmation of Safety of DTaP Vaccines

No new or unexpected adverse events have been detected for diphtheria-tetanus-acellular pertussis (DTaP) vaccines licensed in the U.S., according to a review of close to 20 years of VAERS data, although vaccination errors may have increased.

Bacterial Infection: More Rapid and Accurate Detection

A new study by Waldemar Gorski, professor and chair of the UTSA Department of Chemistry, and Stanton McHardy, associate professor of research in chemistry and director of the UTSA Center for Innovative Drug Discovery, describes a method that could show quickly and accurately whether a person has been infected with harmful bacteria or other pathogens. Additionally, this new method shows the exact severity of infection in a person.

Therepi Enables Delivery of Multiple Therapy Doses To Heart

A team of researchers is hoping to halt the progression from heart attack to heart failure with a small device called 'Therepi.' The device contains a reservoir that attaches directly to the damaged heart tissue. A refill line connects the reservoir to a port on or under the patient's skin where therapies can be injected either by the patient or a healthcare professional. A new study published in Nature Biomedical Engineering

Prevalence of Obesity In the U.S.

After briefly leveling off, the U.S. obesity rate may be climbing again, according to a preliminary study. The rate had been rising for decades until it appeared to plateau in recent years. But, in the new study, researchers found that the trend may have been short-lived. And if nothing changes, they estimate that half of all U.S. teenagers will be overweight or obese by 2030—as will one-third of kids between 6 and 11 years old.