Consciousness is determined both by level and content. Subcortical areas are known to play a causal role in regulating the level of consciousness, but the role of the cortex is less well understood. Researchers are working to identify areas of the brain that help us wake up, a basic building block of everyday consciousness. The study was published in the journal Current Biology.
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Researchers have discovered a new kind of small-cell lung cancer (SCLC). The discovery paves the way for developing personalized medicine approaches to target this previously unnoticed form of the disease.
According to a study, researchers evaluated that physicians' views on advance care planning, goals of care, and end?of?life conversations. While nearly all physicians say end-of-life conversations are important, many reports lacking the training to have such conversations. The study was published in the Journal of the American Geriatrics Society.
Researchers at Oregon State University and Oregon Health & Science University are working on a treatment that holds great promise for improving the lives of cystic fibrosis patients. Findings were published in Molecular Therapy.
A study was to describe transfusion practice in critically ill patients at an international level and evaluate the effects of red blood cell (RBC) transfusion on outcomes in these patients. This was a pre-planned sub-study of the Intensive Care Over Nations audit, which involved 730 ICUs in 84 countries and included all adult patients admitted between 8 May and 18 May 2012, except admissions for routine postoperative surveillance.
Rapid advancements in the field of virtual reality are leading to new developments in cardiovascular treatment and improved outcomes for patients, according to a review paper published today in JACC: Basic to Translational Science. Extended reality applications in cardiac care include education and training, pre-procedural planning, visualization during a procedure and rehabilitation in post-stroke patients.
Protein fragments, called amyloid fibrils, in human semen significantly increase Ebola virus infection and protect the virus against harsh environmental conditions such as heat and dehydration. Researchers from the Perelman School of Medicine at the University of Pennsylvania report these findings in a study published this week in the Proceedings of the National Academy of Sciences (PNAS).
Influenza A (flu A) hijacks host proteins for viral RNA splicing and blocking these interactions caused replication of the virus to slow, according to new research published in Nature Communications by Kristin W. Lynch. Their results also suggest that infection with flu A may reduce splicing of some host genes, which could point to novel strategies for antiviral therapies.
Understanding how and why the human body declines with age and how to slow or prevent it is an extremely important area of research, especially as the older population continues to grow. In addition to providing significant public health benefits, preventing age-related disease could have significant economic impacts on society.
However, aging is difficult to study, as it requires decades and decades of follow-up research. Microgravity offers a solution, as it can serve as a model for accelerated aging. Physiological changes occur approximately 10 times faster in microgravity and it contributes to loss of muscle and bone mass, cardiovascular degeneration, immune deficiency, and optic nerve swelling.
It's been known for years that humans and other mammals possess an antiviral gene called RSAD2 that prevents a remarkable range of viruses from multiplying. Now, researchers have discovered the secret to the gene's success: The enzyme it codes for generates a compound that stops viruses from replicating. The newly discovered compound, described in the online edition of Nature, offers a novel approach for attacking many disease-causing viruses.
Rates of C. difficile infections have decreased 36% in hospitals across Canada, although the virulent NAP1 strain associated with severe illness and deaths is the most common strain, according to research published in CMAJ (Canadian Medical Association Journal)