All news from Anaesthesiology

COPD: Antidepressant Use Increased Mortality Risk

Antidepressant use in people with chronic obstructive pulmonary disease (COPD) is associated with a 20% increase in likelihood of death and a 15% increase in likelihood of hospitalization due to related symptoms, finds a new study led by researchers at St. Michael's Hospital.

Role of PARP Inhibitor in NSCLC

In a randomized, Phase II trial led by researchers at The University of Texas MD Anderson Cancer Center, adding the PARP inhibitor veliparib to a standard chemotherapy agent improved overall response rates (ORR) in patients with small cell lung cancer (SCLC).

Researchers also identified a select group of patients—those whose tumors expressed SLFN11— who also saw a progression-free survival (PFS) and overall survival (OS) benefit, suggesting a promising biomarker for the PARP-inhibitor sensitivity in SCLC.

Osteopathic Manual Therapy In Treating Chronic Low Back Pain

Researchers have verified the effectiveness of a treatment with osteopathic manual therapy including specific techniques on the diaphragm. Researchers recently published a study on patients with chronic non-specific low back pain, where they compared, for the first time in a clinical trial, the effectiveness of a treatment with osteopathic manual therapy with or without specific techniques on the diaphragm.

Astronauts Body Change During Spaceflight

Body Changes Of Astronauts Undergo During Spaceflight

A study observed that there are many changes that occur when an astronaut enters space. Physiological and anatomical changes include bone atrophy, muscle atrophy, and cardiovascular deconditioning occurred in an astronaut’s body during space flight. In addition, space flight leads to dynamic molecular changes within cells. The study was published in NPJ Microgravity, myoblast differentiation can be significantly attenuated by microgravity.