For the first time, scientists have directly visualized real-time structural changes in the surface protein of the influenza virus that may help the virus fuse with and enter target cells before hijacking them. Single molecules of the protein were found to stretch toward target cells, then refold and try again 5 to 10 times per second. The discovery may help develop more effective vaccines and better understand other viruses, including Ebola, HIV, and SARS.
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Researchers showed that the hunt for nitrogen-containing molecules in space. Physicists have discovered frequencies are characteristic of the amide ion, a negatively charged nitrogen molecule. With the spectral lines now determined, this species can be searched for in space.
Researchers have developed a new computational method that increases the ability to track the spread of cancer cells from one part of the body to another. This migration of cells can lead to metastatic disease, which causes about 90% of cancer deaths from solid tumors. Understanding the drivers of metastasis could lead to new treatments aimed at blocking the process of cancer spreading through the body.
A study has found that a new mindfulness-based approach to tinnitus could transform the treatment of the condition. They found that mindfulness-based cognitive therapy(MBCT) helps to significantly reduce the severity of tinnitus compared to relaxation-based treatments, an approach recommended by many tinnitus clinics. The study was published in the journals Ear and Hearing and Psychotherapy and Psychosomatics.
An antioxidant-enriched vitamin may decrease respiratory exacerbations in people with cystic fibrosis (CF), according to new research published online in the American Journal of Respiratory and Critical Care Medicine.
Researchers estimate that Clocking up 45 or more working hours in a week is linked to a heightened risk of diabetes in women. The study published online in the journal BMJ Diabetes Research & Care.
Athletes with shoulder instability injuries often undergo shoulder stabilization surgery to return to sport (RTS) and perform at their preinjury activity level. Returning to sports in a timely fashion and being able to perform at a high level are priorities for these athletes undergoing surgery.
The sexual habits of Trichophyton rubrum, the fungus that causes athlete's foot and other kinds of skin and nail infections, were the focus of a study published by Brazilian scientists and international collaborators in the journal Genetics.
Atopic dermatitis (AD) is a common childhood dermatosis and a distressing cause of morbidity. The pathogenesis of AD is known to be associated with disorders of immune response and defect in antioxidant defense, genetic predisposition, environmental triggers, psychosomatic factors, and other mechanisms. Retinol has immunomodulatory and antioxidant effects, thus may have a protective role in the AD.
Scientists have revealed that immune cells called natural killer (NK) cells may play a key role in ridding the body of malaria-infected blood cells, a study in eLife reports.
People walk into an emergency room because something is wrong. It might be life-threatening or benign. It could cause long-term damage if ignored, or it may be fine to wait out the symptoms. The study primary goals when we see patients in the emergency department are to assess whether the patient is in immediate danger, to stabilize the patient, and then to diagnose if possible.
But sometimes achieving these goals is not enough to meet a patient's expectations. The study was published in the Annals of Emergency Medicine. To better understand the reasons for patient dissatisfaction with ER visits, and to address whether ER physicians are providing care that meets the patients' needs. Researchers engaged 30 individuals who recently visited the ER in open-ended phone discussions and then analyzed their responses by identifying emerging themes.