For the first time, scientists at the Champalimaud Centre for the Unknown (CCU), in Lisbon, Portugal, have shown that neuronal cell death in Alzheimer's disease (AD) may actually not be a bad thing – on the contrary, it may be the result of a cell quality control mechanism trying to protect the brain from the accumulation of malfunctioning neurons. Their results, which were obtained using fruit flies that had been genetically modified to mimic the symptoms of human AD, were published in the journal Cell Reports.
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Physical activity is presumed to decline with the start of adolescence, however, new research shows that this decline begins earlier than previously thought.
Kinetoplastid and apicomplexan parasites include protozoans which are responsible for human diseases, and cause a serious impact on human health and the socioeconomic growth of developing countries. Chemotherapy is the main option to control these pathogenic organisms. The organisms' nuclear metabolism is considered a promising area for the provision of antimicrobial therapeutic targets.
Autophagy is a cellular degradation process that can cause the death of a cell in certain conditions. Autophagy is necessary to maintain cellular homeostasis by clearing out damaged cellular organelles and proteins through certain pathways. Mitochondria are cell organelles responsible for the constant supply of energy to maintain cellular physiology and energy metabolism.
Scientists at Stanford University have designed an electrocatalytic mechanism that works like a mammalian lung to convert water into fuel. Their research, published in the journal Joule, could help existing clean energy technologies run more efficiently.
Living in India and inhaling lungful of polluted air every day is like being a chronic smoker according to a recent report by India’s State-Level Disease Burden Initiative. This partly explains why many people in urban India have a persistent dry and hacking cough even if they don’t have asthma or have never smoked.
University of Queensland researchers have discovered a key mechanism in the brain that may underlie our ability to rapidly focus attention.
For years, the diagnosis of scabies has relied on time-consuming and intrusive full-body examinations. Now, researchers reporting in PLOS Neglected Tropical Diseases have found that an exam of just a patient's hands, feet and lower legs may have the potential to catch more than 90% of all scabies cases, regardless of severity. These speedier exams may be useful in public health assessments on the prevalence of scabies.
A sizable study still can't explain why black Americans are much more likely than whites to suffer sudden cardiac death. "At the end of the day, we just don't have a full understanding of why patients who are black are more likely to succumb to [sudden cardiac death]—a clear problem and knowledge gap on many levels," said study lead author Dr. Rajat Deo.
Under a once controversial, now accepted practice allowing research without patient consent, emergency room doctors at Memorial Hermann’s Texas Medical Center hospital in January will start using an experimental gas in the treatment of unconscious people whose heart suddenly stopped.
Exposure to early life trauma can lead to poor physical and mental health in some individuals, which can be passed on to their children. Studies in mice show that at least some of the effects of stress can be transmitted to offspring via environmentally-induced changes in sperm miRNA levels.
MossRehab, the renowned physical and cognitive rehabilitation arm of Einstein Healthcare Network, has again been named by U.S. News & World Report magazine as a top ten rehabilitation facility in the country for diagnoses including spinal cord injury, stroke, amputation and traumatic brain injury. MossRehab is also once again listed as the top ranked facility of its type in Pennsylvania. This is the twenty-fifth time MossRehab has made the list.