All news from Anaesthesiology

Relationship Between Anatomical And Functional Connectivity Among Muscles

Researchers used network analysis to investigate the relationship between anatomical and functional connectivity among 36 muscles. Human motor control requires the coordination of muscle activity under the anatomical constraints imposed by the musculoskeletal system. Interactions within the central nervous system are fundamental to motor coordination, but the principles governing functional integration remain poorly understood. 

Relaible Way To Know The Formation Of Proteins And Its Activity

According to a study, researchers developed a way to peer inside proteins to see how they are wired. The technique could help scientists develop methods for switching on or off specific proteins associated with diabetes and other diseases. Understanding how a protein is wired could help researchers develop ways to control its activity, and scientists believe they have come up with a reliable way to determine this. The study was published in eLife.

Growth Of Protein Crystals Seen By Cryo-EM

Researchers showed the structure and growth of protein crystals by using Cryo-electron microscopy. They allow to control crystallization and could be used to aid drug formulation. Crystallizing a protein can be a shot in the dark. No one quite knows how protein crystals form, so researchers frequently must use trial and error to find the right crystallization conditions. Scientists have used cryo-electron microscopy (cryo-EM), the technique that took home the 2017 Nobel Prize in Chemistry, to watch the earliest stages of protein crystal formation.

Elders In India Lack Long-Term Palliative care

Researchers conducted a study to survey in India, a large majority of the elderly in India do not get long-term, and palliative care revealed a study conducted for the United Nations. The survey of more than 10,000 respondents across northern, southern, western, eastern, and central India during May-June 2018, showed that 62.1% of the elderly did not get such care. More than half of these people, 52.4%, said they primarily need traditional family support.

U.S. Military Reinvented Trauma Care

According to a study, researchers examine that the U.S. military has reinvented trauma care, offering hope for changing approaches to health care. The study was published online in Health Affairs. Researchers write about the U.S. military's transformation of trauma care experienced over the past 17 years, which included more than 27 major innovations.

ISS Uses Fluorescence Microscope For Live-Cell Imaging In Microgravity

A miniaturized fluorescence microscope makes it possible to observe changes in living cells in microgravity. Future observations of astronauts’ cells could tell scientists important information about how the body adapts to space. NASA reports International Space Station uses miniaturized Fluorescence Microscope to observe changes in Living Cells in Microgravity

An astronaut’s physiology changes during long-duration spaceflight because of the lack of gravity. Knowing the molecular basis of this cellular response to altered gravity is key for risk management, monitoring, and development of countermeasures for future long-term space exploration.

Imaging Live-Cell In Microgravity

Cellular adaptation to the microgravity environment can only be studied and understood in dynamic or live measurements. Live imaging experiments in space are a crucial contribution to the understanding of cellular adaptation to microgravity.

Sticky Protein Promotes The Activity Of Estrogen In Breast Cancer Cells

New research uncovers how a sticky protein called fibronectin promotes the activity of estrogen in breast cancer cells. Together they show a novel mechanism of estrogen receptor signaling that is regulated by fibronectin. They found that exposure to fibronectin prolongs the activity of estrogen receptors in breast cancer cells. Fibronectin rescues estrogen receptor α from lysosomal degradation in breast cancer cells. The study was published in the Journal of Cell Biology (JCB).