All news from Anaesthesiology

Artificial Intelligence System: Prediction of Drug Combinations' Side Effects

Last month alone, 23% of Americans took two or more prescription drugs, according to one CDC estimate, and 39% over age 65 take five or more, a number that's increased three-fold in the last several decades. And if that is not surprising enough, try this one: in many cases, doctors have no idea what side effects might arise from adding another drug to a patient's personal pharmacy.

Macaques with SIV: Gammaherpesviruses linked to Tumors

Viruses known as gammaherpesviruses may raise the risk of cancer in macaques infected with Simian Immunodeficiency Virus or Simian Human Immunodeficiency Virus (SIV/SHIV), according to new research published by Vickie Marshall of the Frederick National Laboratory for Cancer Research, Maryland, and colleagues.

Effectiveness of an Experimental Compound Against Fibrotic Diseases

Normal scar tissue forms to heal an internal wound and quietly retreats when the job is done. But in many common diseases – kidney, liver and lung fibrosis — the scar tissue goes rogue and strangles vital organs. These diseases are largely untreatable and ultimately fatal. A new Northwestern Medicine study has newly identified a trigger of some fibrotic diseases and an experimental compound to treat it.

Low Developmental Screening and Surveillance Rates in the U.S.

Only about one-third of young children in the U.S. receive recommended screenings or surveillance designed to catch developmental delays. Findings reveal wide variations in rates across states, with as few as 17%t of children under three years old receiving developmental screening in the lowest performing state.

The study was led by researchers at the Johns Hopkins Bloomberg School of Public Health, with colleagues at the federal Maternal and Child Health Bureau and Oregon Health & Sciences University.

Fitness Linked to Depression Patient’s Good Health

Exercise may be just as crucial to a depression patient's good health as finding an effective antidepressant. A new study of nearly 18,000 participants found that those with high fitness at middle age were significantly less likely to die from heart disease in later life, even if they were diagnosed with depression.

Astronauts Unconscious Mind Adapting To Microgravity In Space

A study examined that the circadian challenge of astronauts' unconscious mind adapting to microgravity in space, estimated by heart rate variability. It is critical that the regulatory system functions well in space's microgravity. However, the "intrinsic" cardiovascular regulatory system (β), estimated by the fractal scaling of heart rate variability (HRV) (0.0001-0.01 Hz), does not adapt to the space environment during long-duration (6-month) space flights.

Neuroimaging studies suggest that the default mode network (DMN) serves a broad adaptive purpose, its topology changing over time in association with different brain states of adaptive behavior.