All news from Anaesthesiology

Function Of Critical Immune-Surveillance Protein In Humans

Scientists have defined the structure and key features of a human immune-surveillance protein that guards against cancer and bacterial and viral infections. The identification of two human-specific variations in the protein closes a critical knowledge gap in immunology and cancer biology. The study was published in Cell.

Resolving Image In Time By Using STORM

Researchers showed a unique microscopy, Stochastic Optical Reconstruction Microscopy (STORM) is one of the most widely used forms of super-resolution microscopy. Conventional microscopy is limited by the Abbe’s diffraction limit of 250 nm. This means that only objects larger than 250 nm can be resolved.

Super-resolution tools have made it possible to break the diffraction barrier and resolve objects as small as 10−20 nm. STORM, one of the super-resolution techniques invented in 2006, is based on photoswitchable fluorophore or fluorophores which emit light at different times and they are used to resolve the image in time.

Methods To Conquer Sleep Apnea For Place In Bedroom

Researchers examine every night without fail straps on a mask that prevents him from repeatedly waking up, gasping for air. It is been his routine since he was diagnosed with a condition called sleep apnea. While it helps, he does not like wearing the mask. It's been two decades since doctors fully recognized that breathing that stops and starts during sleep is tied to a host of health issues, even early death, but there still isn't a treatment that most people find easy to use.

Overweight Have A Higher Risk Of Developing Type 2 Diabetes

A new study shows that overweight seven-year-olds have a higher risk of developing type 2 diabetes as adults, but only if they are still overweight by the time they hit puberty and beyond. It's well known that overweight in childhood leads to an increased risk of type 2 diabetes later in life.

Our research has previously shown that children who weigh just a couple of kilograms too much have a much higher chance of developing the disease and that this effect is more pronounced in girls than boys. The study was published in the New England Journal of Medicine.

Steps For Lifesaving CPR

More than 350,000 people had sudden cardiac arrest outside of a hospital in 2017. Those who received CPR were two to three times more likely to survive. It is a moment everyone hopes they never experience, but it could happen at any time: finding a person in cardiac arrest unconscious and nonresponsive.

Circadian Rhythms Depends On Neuropeptide Release Of VIP SCN Neurons

Scientists unlocked a cure for jet lag in mice by activating a small subset of the neurons involved in setting daily rhythms. The mammalian suprachiasmatic nucleus (SCN) functions as a master circadian pacemaker, integrating environmental input to align physiological and behavioral rhythms to local time cues. The study was published in the journal Neuron.

Approximately 10% of SCN neurons express vasoactive intestinal polypeptide (VIP); however, it is unknown how the firing activity of VIP neurons releases VIP to entrain circadian rhythms. To identify physiologically relevant firing patterns, they optically tagged VIP neurons and characterized spontaneous firing over 3 days.  VIP neurons had circadian rhythms in firing rate and exhibited two classes of instantaneous firing activity.