A study aims to analyze the relationship between maternal type 1 diabetes and the offspring’s metabolic health and investigate whether birthweight and/or changes in the offspring’s metabolome are in the potential pathway. Children of mothers with type 1 diabetes are at significantly higher risk of being overweight and of exhibiting insulin resistance. The study was published in the journal Diabetologia.
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A study showed that cancer patients receiving anti-PD-1 therapies who develop lesions, eczema, psoriasis, or other forms of autoimmune diseases affecting the skin may experience those adverse reactions on a delay sometimes even after treatment.
In a study that provides guidance for physicians and has implications for patient counseling dermatologists in the Perelman School of Medicine at the University of Pennsylvania found patients developed skin disease a median of four months after starting treatment, though in one case, the effects were not observed until more than three years later. The study was published in JAMA Dermatology.
A clinical trial of the use of adrenaline in cardiac arrests has found that its use results in less than 1% more people leaving the hospital alive, but almost doubles the risk of severe brain damage for survivors of cardiac arrest. The research raises important questions about the future use of adrenaline in such cases and will necessitate debate amongst healthcare professionals, patients, and the public. The study was published in the New England Journal of Medicine (NEJM), A Randomized Trial of Epinephrine in Out-of-Hospital Cardiac Arrest.
Genentech has announced that baloxavir marboxil met the primary objective and showed superior efficacy in the primary endpoint of time to improvement of influenza symptoms compared with placebo in phase 3 CAPSTONE-2 study assessing the safety and efficacy in individuals with a high risk of complications from the flu.
A jewel addition to the Nepal’s health care facilities is the ‘Aama Surakshya’ (protection of mothers) program established in 2005
Psychologists have devised a novel psychological intervention to address anxiety in bipolar disorder (AIBD). Anxiety is common in bipolar disorder (BD) and associated with worse clinical outcomes including increased suicidality. Despite effective psychological treatments for anxiety, research into treating anxiety in BD is underdeveloped.
In a significant consumer-friendly move, insurance regulator Irdai said it has started the exercise to minimize the number of illness/diseases which are not covered under the health insurance policies.
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality and also contributes to huge health care expenditures in China. Therefore, accurate and early identification of high-risk individuals is important for CVD prevention. The China-PAR (Prediction for atherosclerotic CVD (ASCVD) Risk in China) project generated equations with excellent capacity to predict lifetime risk for ASCVD by incorporating four large and ongoing cohorts followed up until 2015 with 106,281 Chinese participants, according to a new study published by Science Bulletin.
Two concurrently published studies with dupilumab (Dupixent) have evidenced its efficacy and safety in moderate-to-severe uncontrolled asthma, and in reducing steroid requirement in previously glucocorticoid-dependent severe asthma. The study is was published online in The New England Journal of Medicine.
Breathlessness and conditions of restrictive lung disease (RLD), such as pulmonary fibrosis, may be a late complication of type 2 diabetes. The latest results have been published in the journal Respiration.
A new special issue of SLAS Discovery reflects examples of the recent groundswell of creative new applications for high-throughput flow cytometry (HTFC) in drug discovery.
Scientists have developed a chip that can detect a type of genetic mutation known as a single nucleotide polymorphism (SNP) and send the results in real time to an electronic device. The chip is at least 1,000 times more sensitive at detecting an SNP than current technology. The advance, published in Advanced Materials, could lead to cheaper, faster and portable biosensors for early detection of genetic markers for diseases such as cancer.