All news from Anaesthesiology

A Single-Cell Atlas of the Lung Cell

In separate studies published online in Nature, two independent research teams report the discovery of a new, rare type of cell in the human airway. These cells appear to be the primary source of activity of the CFTR gene, mutations to which cause cystic fibrosis, a multiorgan disease that affects more than 70,000 people worldwide.

Improving Cardiac Arrest Survival In Hospitals

Among the many new responsibilities these young doctors will be taking on, one of the oldest and most critical will be their role on Code Blue teams or groups of caregivers who respond to cardiac arrests. About 200,000 cardiac arrests happen each year in U.S. hospitals. Nearly 80% of patients do not survive.

After collecting and reviewing nearly 80 hours of interviews, we found striking and humbling results: Top hospitals designed, deployed and trained their Code Blue teams, which respond to cardiac emergencies, in fundamentally different ways. The study was published recently in Circulation, a journal of the American Heart Association.

Urine-Based Diagnostic for Cystic Fibrosis, Clinical Trials

Mologic Ltd, a developer of powerful, personalized diagnostics to improve the lives of patients, today announced that it has commenced a clinical trial to evaluate the Company's urine-based diagnostic, HeadsUp, in monitoring pulmonary exacerbation in cystic fibrosis (CF) patients.

The study aims to identify five urinary biomarkers associated with the onset of the pulmonary exacerbation in adults with CF. It will also validate the use of the novel point-of-care (POC) test for patient's self-monitoring of their condition.

Nanostructured Sensor System: Brain Aneurysm Treatment Monitored

Implantation of a stent-like flow diverter can offer one option for less invasive treatment of brain aneurysms – bulges in blood vessels – but the procedure requires frequent monitoring while the vessels heal.

Now, a multi-university research team has demonstrated proof-of-concept for a highly flexible and stretchable sensor that could be integrated with the flow diverter to monitor hemodynamics in a blood vessel without costly diagnostic procedures. The research was reported in the journal ACS Nano.

Being overweight May Change Young Adults' Heart Structure , Function

According to a new study, the research examined that a higher body mass index (BMI), a weight-for-height index results in adverse effects on the cardiovascular system in young adults. Even as a young adult, being overweight may cause higher blood pressure and thicker heart muscle, setting the stage for heart disease later in life. The study was published in the American Heart Association's journal Circulation.

Duration of Shedding of Influenza A Virus Linked with Obesity, Study

Obesity, which increases influenza disease severity, also extends by about 1.5 days how long influenza A virus is shed from infected adults compared to non-obese adults, according to a multi-year study of two cohorts of Nicaraguan households. The findings implicate chronic inflammation caused by obesity as well as increasing age as reasons for extended viral shedding, which puts others at risk of infection.