All news from Anaesthesiology

Scanning Tunneling Microscopy Imaging Molecule-Covered Surface Structures

A study determined that by using scanning tunneling microscopy (STM), extremely high-resolution imaging of the molecule-covered surface structures of silver nanoparticles is possible, even down to the recognition of individual parts of the molecules protecting the surface. Real-space imaging with pattern recognition of a ligand-protected Ag374nanocluster at a sub-molecular resolution. The study was published in Nature Communications.

Factors Contributing To Geographic Variation In End-Of-Life Costs For Cancer Patients

According to a study, researchers examined the extent to which variation in health care spending in the months before death is explained by differences in patients' sociodemographic factors, clinical factors, and beliefs; physicians' beliefs; and service availability. Geographic variation in end-of-life spending can be explained by the availability of services and physicians' beliefs, but not patients' beliefs. The study was published in the Health Affairs.

New Treatment For A Severe Lung Disease

Scientists at Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago took a major step toward developing a new treatment for pulmonary arterial hypertension (PAH), a severe lung disease with a five-year survival rate of 50%.

They identified a drug with a positive safety profile that inhibits a gene called HIF-2α, which they discovered earlier promotes the progressive thickening of the lung artery walls, a key feature of PAH called "vascular remodeling," which leads to right-sided heart failure, the main cause of death in PAH patients.

Recently, they demonstrated in three clinically-relevant animal models that inhibiting HIF-2α with a compound results in reversal of established PAH, suppression of vascular remodeling and right heart failure, and increased survival. The study was published in the American Journal of Respiratory Critical Care Medicine.

Skin Disease Affects Based On Skin Conditions

Although skin disease can affect anyone, it may not affect everyone in the same way and this is especially true for patients with skin of color. Skin conditions are color blind, occurring in patients of every skin tone, but certain conditions can affect patients with skin of color more frequently and more severely.

Skin Treatments

Moreover, certain dermatologic treatments may cause problems in this population if those treatments aren't performed properly by a qualified, experienced physician like a board-certified dermatologist.