All news from Health & Hospital Administration

Hospital Stay Serves Large Numbers Of Cardiac Patients

When Medicare in 2011 agreed to pay for a revolutionary procedure to replace leaky heart valves by snaking a synthetic replacement up through blood vessels, the goal was to offer relief to the tens of thousands of patients too frail to endure open-heart surgery, the gold standard.

To help ensure good results, federal officials limited Medicare payment only to hospitals that serve large numbers of cardiac patients. The strategy worked. In the past seven years, more than 135,000 mostly elderly patients have undergone transcatheter aortic valve replacement, known as TAVR. And TAVR's in-hospital mortality rate has dropped by two-thirds, to 1.5%.

Structure In Lymph Nodes Are Identified By Photon Microscopy

Researchers have identified a new 'micro-organ' within the immune system and they say it's an important step towards understanding how to make better vaccines. They have identified where the immune system 'remembers' past infections and vaccinations and where immune cells gather to mount a rapid response against an infection the body has seen before. The study was published this week in Nature Communications.

Regulation Of Energy Rheostasis By The Melanocortin-3 Receptor

Scientists have identified the function of a protein that has been confounding metabolism researchers for more than two decades. And it may have implications both for treating obesity and for understanding weight gain during pregnancy and menopause.

The protein, called the melanocortin 3 receptor (MC3R) maintains what Roger Cone, director of the U-M Life Sciences Institute, has termed "energy rheostasis," a poorly understood phenomenon in the field of metabolism research.

A lack of MC3R has almost no effect on mice under normal conditions. But when their metabolism is challenged, mice without this protein lose more weight when fasting and gain more weight when eating a high-fat diet, compared with normal mice.

Cerebral Stroke After Surgery Leads To Blood Flow

The researcher showed that a patient suffered a cerebral stroke after his parents failed to recognize a warning sign for a disorder related to blood flow, recovering after brain surgery at AMRI Hospitals Dhakuria. They had a seizure in sleep one-and-a-half years ago, woke up and started shrieking, complained of a severe headache and was unable to recognize his parents for a while.

Safety Of Discharging Patients From ICU

According to a study, researchers examined that the safety of discharging adult patients recovering from a critical illness directly home from the intensive care unit (ICU) is unknown. Direct discharge home from the ICU does not increase health care utilization or mortality. The study was published in JAMA Internal Medicine.

Drug Improving Liver Cancer Therapy

Researchers from many international institutions have teamed up to design a more effective drug for liver cancer therapy. Their compound may help improve survival rates and reduce adverse effects. Hepatocellular carcinoma, or primary liver cancer, tend to grow and expand at a fast rate.

If it is not caught early, this means that people who have been diagnosed with it may not survive longer than 11 months. Recent studies show that in the United States, hepatocellular carcinoma is the ninth leading cause of cancer-related deaths. The study was published in the journal PNAS.

Major Trauma Patients And Their Outcomes In The NHS

The NHS in England has saved an additional 1,600 patients with severe injuries since major trauma centers were established in 2012. New findings show the creation of major traumas centers has led to the survival of more than 1,600 patients who have suffered some of the most severe and complicated injuries thanks to top teams of surgeons, doctors, and clinical staff. Patients also spent fewer days in the hospital and had improved quality of life after receiving critical care.

The independent report, which features in the latest issue of Eclinical medicine published by The Lancet, has been compiled by the Trauma Audit and Research Network (TARN) based at The University of Manchester supported by experts at the Universities of Leicester and Sheffield.

Association Between Physical Therapy And ED Revisits for Older Adults

Falls are the leading cause of illness and death among Americans aged 65 and older. In 2014, some 2.8 million older adults visited the emergency department (ED) for a fall-related injury. And over time, the ED visit rate for falls among older adults has grown to 68.8 per 1,000 older adults (as of 2010).

Older adults who visit the ED for a fall are at high risk for both revisiting the ED and dying. In fact, some estimates show that 25 percent of older adults visiting the ED for a fall returned for at least one additional fall-related visit. Fifteen percent of those older adults died within the following year.

Resignation Syndrome Affecting Refugee Children

The researcher examined the raising concerns about an outbreak of a severe trauma-related mental disorder known as traumatic withdrawal syndrome, or resignation syndrome. The recent legal action resulted in the urgent medical evacuation of a child in an unconscious state following a progressive social withdrawal and failure to speak, eat or drink. The child was unresponsive, dehydrated and at risk of death from the physical complications of this extreme state.

Systemic Thyroid Hormone Status During Levothyroxine Therapy In Hypothyroidism

A study of overt hypothyroidism in which participants were treated with levothyroxine to normalize serum TSH levels and measured other objective markers of thyroid hormone signaling. The standard of care for overt hypothyroidism is levothyroxine at doses that normalize serum TSH levels. Whether this approach universally restores thyroid hormone signaling is unknown. The study was published in The Journal of Clinical Endocrinology & Metabolism.