All news from Physical Medicine & Rehabilitation

Research Finds New Channel-gating Mechanism

Computational biophysicists are not used to making discoveries, says Jianhan Chen at the University of Massachusetts Amherst, so when he and colleagues cracked the secret of how cells regulate Big Potassium (BK) channels, they thought it must be a computational artifact. But after many simulations and tests, they convinced themselves that they have identified the BK gating mechanism that had eluded science for many years

A Novel Imaging Technique For Mapping Metabolism

Yale researchers have developed a new imaging technique that captures detailed information about metabolism, which plays a role in many diseases. The novel yet simple technique, which harnesses existing technology, could potentially be used to evaluate the effectiveness of drug therapies for cancer and other conditions, the researchers said

Air Pollution Can Fuel Kidney Disease

There is good evidence that polluted air increases the risk of respiratory problems such as asthma—as well as organ inflammation, worsening of diabetes and other life-threatening conditions. But new research suggests air pollution can also fuel something else: chronic kidney disease, or CKD, which occurs when a person's kidneys become damaged or cannot filter blood properly