Researchers have shown that the use of chemically-modified DNA aptamers as protein markers allows one to enhance the power of super-resolution fluorescence microscopy as an imaging tool.
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Patients need to be in a hopeless state of constant and unbearable physical or mental pain that cannot be alleviated, or suffering as a result of a serious and incurable disorder caused by an accident or illness. Since 2002 Belgium has been one of the very few countries in the world in which doctors can perform euthanasia.
Researchers evaluate the characteristics of physician empathetic statements during pediatric intensive care unit care conferences. Physicians express empathy frequently to families in the pediatric intensive care unit, but more than one-third of empathetic statements are buried by medical jargon that reduces their effectiveness.
In nearly every intensive care unit (ICU) at every pediatric hospital across the country, physicians hold numerous care conferences with patients' family members daily. Due to the challenging nature of many these conversations covering anything from unexpected changes to care plans for critically ill children to whether it's time to consider withdrawing life support these talks tend to be highly emotional.
Researchers have used some of the most advanced sequencing technology to peer into nasal polyps, gleaning new insights not only into this condition but also the severe form of inflammation that may lead to other disorders, such as asthma, allergic rhinitis, and allergic eczema. The study was published in Nature.
A novel drug is being touted as a major step forward in the battle against Australia's escalating rates of obesity and associated metabolic diseases. As it stands, 2 in 3 adults in Australia are classified as being overweight or obese.
A long-term study between researchers at the Centenary Institute and UNSW Sydney has led to the creation of a drug which targets an enzyme-linked to insulin resistance a key contributor of metabolic diseases, such as Type II diabetes.
Together, they set out to create a drug that targeted enzymes within the Ceramide Synthase family, which produce lipid molecules believed to promote insulin resistance in skeletal muscle, as well as liver and fat tissue. The study was published in the highly-regarded scientific journal Nature Communications.
Researchers estimated the patient-reported burden of the AD with regard to the impact of disease severity and inadequate control in adults from clinical settings. Real-world data are limited on the patient-reported burden of adult atopic dermatitis (AD).
Hospitals have seen record demand for care over recent days as the winter season takes full effect, with 2600 people presenting at EDs last week compared with 2450 at the same time last year, adding 150 patients to what was already a very busy period. Chief Medical Officer Dr. Andrew Brant says heavy demand for inpatient hospital care makes it all the more important that hospital resources are prioritized toward those in greatest need.
According to researchers, one night of sleep loss has a tissue-specific impact on the regulation of gene expression and metabolism in humans. This may explain how shift work and chronic sleep loss impairs our metabolism and adversely affects our body composition.
In a new study, researchers demonstrate that one night of sleep loss has a tissue-specific impact on the regulation of gene expression and metabolism in humans. This may explain how shift work and chronic sleep loss impairs our metabolism and adversely affects our body composition. The study was published in the scientific journal Science Advances.
Researchers aimed to identify which symptoms were the best predictors of an ADHD diagnosis and the likelihood of receiving medication and whether these differed between boys and girls. Asked what they know about attention-deficit hyperactivity disorder or ADHD, many people will likely tell you that it mostly affects children, and mostly boys.
However, recent research has shown that neither of these perceptions is entirely true. There is a striking difference in the sex of children diagnosed with ADHD, with boys more likely to be diagnosed than girls (the ratios can be as high as 9:1 in some studies). The study was published in the European Journal of Child and Adolescent Psychiatry.
However, these studies are of children who have an established diagnosis of ADHD, and such estimates are affected by referral patterns, so they may not reflect the true sex ratio.
Over the last decade, it's become clearer than ever that bacteria in the human gut — collectively termed the microbiome — play a key role in health and disease. Now, researchers reporting in PLOS Neglected Tropical Diseases have shown that a subset of people with soil-transmitted helminth infections have changes to their microbiome when treated for the infection.
Daily antiretroviral therapy (ART) that suppresses HIV to levels undetectable by standard blood tests is lifesaving for individuals living with HIV and prevents sexual transmission of the virus to others.
The public health community must use targeted interventions, however, to do a better job of reaching populations with low levels of viral suppression, according to experts from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health.
When patients presented with unexplained fever at Mwananyamala Hospital in Dar es Salaam, Tanzania, scientists compared two genetic sequencing methods used to identify the potential viruses behind the illnesses: VirCapSeq-VERT, a method developed at the Center for Infection and Immunity (CII) and unbiased high-throughput sequencing.
Both methods yielded similar results. However, VirCapSeq-VERT was more efficient. Details of the study, the first to report on the use of VirCapSeq-VERT in a clinical setting, are published today in the journal mSphere.