All news from Anaesthesiology

Association Between High-sensitive Troponin And CV Using CMR

Researchers have now able to show that cardiac damage can be diagnosed in a patient-friendly way by heart imaging- ahead of the clinical symptoms.Systemic inflammatory diseases, such as lupus, often cause cardiac damage that goes undetected.

The number of diagnoses of systemic lupus erythematodes (SLE) has tripled over the past 45 years due in part to improved diagnostic methods. Lupus is a systemic inflammatory disease which can affect several organs; most frequently the kidneys, skin, brain and the heart. Involvement of the heart is important as it determines these patients' outcome, yet as it carries on silently for a long time, it may go undetected and untreated for a long time.

Specilized Neurons For Proper Breathing Rhythms At Birth

The common expression, 'As easy as breathing,' is truly misleading. Breathing, as it is performed by higher vertebrates, is a complex biological function involving many types of neurons. It requires chemosensory neurons to sense oxygen and carbon dioxide levels in the blood and motor neurons to control muscle movement.

It also needs specialized neurons to establish correct breathing rhythms at birth and subsequently maintain it throughout life. The mechanism by which actions of these diverse groups of neurons are finely orchestrated to produce precise breathing rhythms has remained a mystery. The study was published in the journal eLife.

No Accuracy from Mouse Models in Mimicking Severity of Gonorrhea Infection, Findings

There is an urgent need to develop a vaccine to prevent gonorrhea infection due to rapidly increasing incidence and growing antibiotic resistance.

BUSM researchers have been investigating the use of animal models of gonorrhea, to study how the infection evolves and for potential use to determine the efficacy of next-generation vaccines. They found that the mouse model may not fully reflect the severity of the infection and the types of immune responses seen in humans.

'Jumpstart' Rhythmic Breathing at Birth, Mechanism Elaborated

The common expression, 'As easy as breathing,' is truly misleading. Breathing, as it is performed by higher vertebrates, is a complex biological function involving many types of neurons. It requires chemosensory neurons to sense oxygen and carbon dioxide levels in the blood and motor neurons to control muscle movement.

It also needs specialized neurons to establish correct breathing rhythms at birth and subsequently maintain it throughout life. The mechanism by which actions of these diverse groups of neurons are finely orchestrated to produce precise breathing rhythms has remained a mystery. The study is published in the journal eLife.

Influenza A virus Subtype: Effectiveness of Synthetic DNA Vaccine

Currently available vaccines for the prevention of seasonal influenza virus infection have limited ability to induce immunity against diverse H3N2 viruses, an influenza A subtype that has led to high morbidity and mortality in recent years. Now, scientists have engineered a synthetic DNA vaccine shown to produce broad immune responses against these H3N2 viruses.

Fight of Multidrug-Resistant Tuberculosis, Novel Approaches

Several new medicines have been found to be more effective than traditional ones used to treat multidrug-resistant tuberculosis (MDR-TB), according to a new international collaborative study led by Dr. Dick Menzies, senior scientist. These findings precipitated a complete overhaul of worldwide TB treatment guidelines, with the results of this work published today in the British medical journal The Lancet.

Cancer Cells Killed with Bioadhesive, Wirelessly-Powered Implant, Findings

A new wirelessly-powered light-emitting device, which sticks onto animal tissue like a sticker with tissue-adhesive and elastic nanosheets, could possibly facilitate treatment for hard-to-detect microtumors and deeply located lesions that are hard to reach with standard phototherapy.

If clinically applied, the device could be beneficial for cancer patients who seek minimally invasive treatment, helping them live longer and improve their quality of life.