The imaging method called cryo-electron microscopy (cryo-EM) allows researchers to visualize the shapes of biological molecules with an unprecedented level of detail. Researchers used cryo-EM to show the structure of a version of a virus called an AAV2, advancing the technique’s capabilities and the virus’ potential as a delivery vehicle for gene therapies. The study was published in Nature Communications.
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It is not always easy to see if a switch is on or off! A new study shows that the same can be true of a molecular switch. This knowledge gives a new insight into the molecular switches, the GTPases, many of which have medical potential.
Around one percent of people infected with HIV produce antibodies that block most strains of the virus. These broadly acting antibodies provide the key to developing an effective vaccine against HIV. Researchers have now shown that the genome of the HI virus is a decisive factor in determining which antibodies are formed.
Benzodiazepines pose special risks to older adults. New research finds many of those who start taking them aren’t stopping. They may start as temporary, well-intentioned efforts to calm anxiety, improve sleep or ease depression. But prescriptions for sedatives known as benzodiazepines may lead to long-term use among 1 in 4 older adults who receive them, according to new research. The study was published in JAMA Internal Medicine.
Changing the way tobacco is sold is a crucial step in achieving the Government's 2025 smoke-free goal, new University of Otago research suggests. If the Government prevented new retail outlets from selling tobacco while allowing existing retailers to continue selling tobacco until they closed or relocated, it could achieve a 50% reduction in tobacco outlets by 2032, the research just published in the medical journal Tobacco Control shows.
By developing a novel decoding technology, a team of engineers and physicians at the University of Southern California (USC) and UC San Francisco have discovered how mood variations can be decoded from neural signals in the human brain, a process that has not been demonstrated to date. The study was published in Nature Biotechnology.
It is a significant step towards creating new closed-loop therapies that use brain stimulation to treat debilitating mood and anxiety disorders in millions of patients who are not responsive to current treatments.
Among 5,919 patients with symptoms of suggestive parasite infections, study found that at least 124 people suffer from intestinal parasite infection. The study conducted by officials of the Jigme Dorji Wangchuck National Referral Hospital (JDWNRH) used samples of 5,919 patients between 2013 and 2015.
The samples collected were from the patients visiting JDWNRH with the symptoms of suggestive parasite infections. The study found that the overall prevalence rate was 2.1%.
New model suggests natural healing cycle becomes blocked by cellular miscommunication, allowing conditions like cancer, diabetes and some neurological disorders to persist; a small but dramatic autism trial offers evidence.
The present study deals with examining factors that catalyze demand for community-based micro health insurance (MHI) schemes. We hypothesize that demand for health insurance is a collective decision in the context of informality and poverty.
Our hypothesis challenges the classical theory of demand which posits individual expected diminishing utility. We examine factors beyond the traditional exogenous variables.
The Nash County Home Health Agency may have been sold recently to a third-party provider, but the Nash UNC Health Care Hospice and Palliative Care program is still doing business the way it has been doing for more than 30 years.
“I think some people were confused by the coverage of the recent sale of the Home Health Agency, but we are still a part of Nash UNC Health Care,” said Sherri Alligood, director of the Hospice and Palliative program, which has been owned by the hospital for more than 30 years.
Dr.Doulgas Boyette is the medical director of the program that provides home care for patients whose doctors certify they need end-of-life care for the remaining months of their lives. These services can be provided at home or a nursing facility.
The number of people living with asthma has nearly doubled over the last 40 years, according to the National Health Interview Survey, and Southeast Georgia is no exception. But, thanks to recent scientific breakthroughs, there’s a new procedure that has the potential to dramatically improve the quality of life for people who have trouble controlling their asthma.
According to a study, researchers examine the temporal change and susceptible periods for cardiovascular complications in patients recovering from sepsis by using a national database. Patients with sepsis are at increased risk of stroke or myocardial infarction (heart attack) in the first 4 weeks after hospital discharge. The study was published in the CMAJ (Canadian Medical Association Journal).