All news from Anaesthesiology

Syphilis: Early Test All Pregnant Women Says USPSTF

All pregnant women should undergo early screening for syphilis, according to an updated recommendation statement from the US Preventive Services Task Force (USPSTF). This newest guidance reaffirms the statement published in 2009 and is an "A" recommendation, which means there is high certainty of a substantial net benefit.

Public Policy Education: 'Indian Students need to Develop Skills for its Application'

Public Policy has always been close to Paul Kelly's heart and gets him talking enthusiastically. On a recent visit to India, Kelly, who is pro-director for International Partnerships and East Asia and professor of Political Theory, London School of Economics and Political Science (LSE), feels Indian students need to develop skills for policy application, in a sense, policy entrepreneurship and the character that goes with it – involving critical engagement, being an independent learner and the ability to use relevant knowledge.

Aging Reduces Intermittent Hypoxia-induced Lung Carcinoma Growth

A scientific study, conducted with animal models, states that sleep apnea can favor lung cancer growth in young individuals. Thus, aging would be a protecting factor against the fast tumor development, induced by this sleep alteration The study was published in the journal Americal Journal of Respiratory and Critical Care Medicine,

It has been carried out by research teams led by the lecturers Ramon Farré, from the Faculty of Medicine and Health Sciences and the Institute of Nanoscience and Nanotechnology (IN2UB) of the University of Barcelona, and Josep María Montserrat, from the same Faculty and Hospital Clínic de Barcelona, also linked to the Respiratory Diseases Networking Biomedical Research Centre (CIBERES).

Concussions: Insulation Around Brain Cells Disrupted

Detailed scans of concussed hockey players found that the protective fatty tissue surrounding brain cell fibers was loosened two weeks after the injury — even though the athletes felt fine and were deemed ready to return to the ice. A loosening of that insulation, called myelin, slows the transmission of electrical signals between neurons, and shows that passing a concussion test may not be a reliable indicator of whether the brain has truly healed.

ER Stress Drives Lipogenesis and Steatohepatitis via Caspase-2 Activation of S1P

Researchers have discovered using mice and human clinical specimens, that caspase-2, a protein-cleaving enzyme, is a critical driver of non-alcoholic steatohepatitis (NASH), a chronic and aggressive liver condition.

By identifying caspase-2's critical role, they believe an inhibitor of this enzyme could provide an effective way to stop the pathogenic progression that leads to NASH and possibly even reverse early symptoms. The findings are published in the September 13 online issue of Cell.

Molecules May Increase Cardiovascular Risk From Early Life Stress

The release of "danger" molecules in response to significant periods of mental stress early in life may leave young people at lifelong risk of cardiovascular disease. They know mental stress is bad for the cardiovascular system.

They want to know more about how it's bad. They think one answer is DAMPs, or damage (AKA "danger") associated molecular patterns. Stressed and dying cells regularly empty their contents or DAMPs.