All news from Anaesthesiology

Tumor Cell Expansion Challenges Current Physics

A malignant tumor is characterized by its ability to spread around its surroundings. To do so, tumor cells stick to the surrounding tissue (mainly collagen) and use forces to propel. The study was published in the journal Nature Physics. They reveal the forces these tumor cells use to spread. The relation between these forces and the cell movement goes beyond current physical laws.

Recurrent Cortical Circuits Implement Concentration-Invariant Odor Coding

If you can tell the difference between a merlot and a cabernet franc just by smell, it's probably all in the timing. That's because the odor-decoding centers of the brain will pay more attention to the first smell signals to reach them, regardless of how long or strong the remainder of the sniff may be, they have teased apart the neural circuitry of smell in mice. The study was published in Science.

Rapid Genomic Sequencing To Diagnose Critically Ill Children With Diseases

A multidisciplinary team at KK Women's and Children's Hospital (KKH) has developed a test to enable faster diagnosis of rare diseases to help critically ill children. Rapid genomic sequencing or RapidSeq of critically ill children in the neonatal and children's intensive care units is a test, the first of its kind in Singapore, to provide information on the underlying genetic diagnosis of these critically ill children.

Novel, Palatable Paediatric Oral Formulation Of Midazolam

Researchers have developed a winning medicine formula that makes bad-tasting medicine taste nice, making it easier to treat sick children. The study published by the journal Anaesthesia tested 150 children and found that the majority of children who were given the new chocolate-tasting medicine would take it again, unlike the standard treatment, while they still experienced the same beneficial effects.

Type 2 diabetes Genetic loci Associations Point To Disease Mechanisms And Subtypes

Most patients with type 2 diabetes are treated with a 'one-size-fits-all' protocol, but this approach can leave many cases inadequately managed. New work indicates that inherited genetic changes may underlie the variability seen among diabetes patients, with different physiological processes potentially leading to high blood sugar.

This work represents a first step toward using genetics to identify subtypes of type 2 diabetes. The study was published in PLOS Medicine. Most patients diagnosed with type 2 diabetes are treated with a "one-size-fits-all" protocol that is not tailored to each person's physiology and may leave many cases inadequately managed.