Switching off the enzyme that adds protective caps to chromosome ends could help fight many types of cancer, A*STAR researchers have shown. The team demonstrated the treatment's potential by using it to thwart tumor growth in mice.
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Heart disease has been the leading cause of death in the United States for more than a century, ever since the early 1900s when it displaced acute diseases for the distinction. Now a growing number of states are crowning a new leading cause of death: cancer.
The number of people living with dementia globally more than doubled between 1990 and 2016 from 20.2 million to 43.8 million, prompting researchers to call for more preventative action. A new paper published in The Lancet Neurology also found that 22.3% of healthy years lost due to dementia in 2016 were due to modifiable risk factors.
University of Nebraska-Lincoln researchers may have identified a vaccine that would defend against Zika virus without producing antibodies. Researcher Eric Weaver described the finding as exciting and novel. He and his team are confident that future experiments will yield significant findings that could have a profound impact on the field of vaccinology.
Researchers at the University of Sussex have created the fastest and most energy efficient simulation of a mouse brain using off-the-shelf computer hardware . Dr James Knight and Prof Thomas Nowotny from the University of Sussex's School of Engineering and Informatics have published the top 50 supercomputers by running brain simulations using their own GeNN software and Graphics Processing Units (GPUs).
In 2015, then President Barack Obama launched a precision medicine initiative, saying that its promise was "delivering the right treatments, at the right time, every time to the right person."
A team of researchers with members from the Netherlands and the U.S. has found differences in the numbers of gut microbes for patients with inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS).
In their paper published in the journal Science Translational Medicine the group describes how they sequenced the genome of gut microbes in patients with bowel problems and what they found.
Dementia is common to a variety of neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson's disease (PD) and Down syndrome (DS). This characteristic symptom is one of the significant causes of disability and dependency among older people. Worldwide, around 50 million people have dementia, and there are nearly 10 million new cases every year.
Scientists have taken a key step toward improving an emerging class of treatments for Parkinson's disease. The advance could markedly improve the next generation of therapies for the condition, which affects around one in 350 people in the UK.
A new study led by researchers at the Columbia Center for Children's Environmental Health (CCCEH) organizes the available scientific evidence on the effects of air pollution on children's health.
A new compound that inhibits the replication of hepatitis C virus (HCV) in several stages of its lifecycle – and is capable of acting on bacteria, fungi, and cancer cells – has been synthesized by researchers at São Paulo State University (UNESP) in Brazil