All news from Trauma and Critical Care Medicine

One In Four ALD Patients Return To ICU

Two in three ALD patients admitted to an intensive care unit (ICU) survived for less than a year afterward. The findings highlight the need for increased support for ALD patients after they leave the hospital.

The study was published in Critical Care Medicine. The number of intensive care admissions for ALD are increasing in the UK but, until now, little was known about the long-term consequences for patients following time spent in critical care.

Researchers at the University of Edinburgh looked at anonymized records of over 8000 ICU admissions in Scotland over six years to make their findings. Their study is the first to create a snapshot of ALD patients for a nation.

Genetic Code Is Dormant In Astronauts During Hibernation

Bears do it. So do groundhogs, squirrels, turtles, and many other animals. Humans, however, can’t hibernate at least not right now. But scientists exploring the genetic underpinnings of hibernation in animals think they may be able to unlock the same biological superpower in humans.

That feat could transform medical care during both routine surgeries and dire medical emergencies when patients cannot immediately get access to lifesaving treatment. It could also make it possible for astronauts to snooze their way on long missions to Mars and other destinations in deep space.

Systematic Review & Meta?analysis Of Ketamine as an Alternative to Opioids for Acute Pain In The ED

Intravenous, low-dose ketamine (LDK) is as effective as intravenous morphine in the control of acute pain in adults in the emergency department (ED). The study was published in the issue of Academic Emergency Medicine (AEM), a journal of the Society for Academic Emergency Medicine (SAEM). The results indicate that ketamine can be considered as an alternative to opioids for ED short-term pain control.

New Insights Into Gene Underlying Circadian Rhythms

Innovative cardioprotective strategies are of imminent demand. Nonfatal myocardial ischemia (MI) poses a significant risk to patients undergoing major non-cardiac surgery and these non-cardiac surgeries account for around 8 million myocardial injuries per year.

Considering perioperative MI is the most common major cardiovascular complication, identifying factors that lead to cardiac disease onset and finding solutions to prevent potential cardiac damage is of critical importance.

Previous work revealed that anesthetics used in the perioperative setting alter the cellular circadian biology and furthermore, a critical role for the circadian rhythm protein Period 2 (PER2) was revealed in promoting cardioprotection through metabolic pathway mediation.

Reduced Mortality with Increased Cardiorespiratory Fitness, Experts Find

Cleveland Clinic researchers have found that better cardiorespiratory fitness leads to longer life, with no limit to the benefit of aerobic fitness. Researchers retrospectively studied 122,007 patients who underwent exercise treadmill testing at Cleveland Clinic between Jan. 1, 1991, and Dec. 31, 2014, to measure all-cause mortality relating to the benefits of exercise and fitness. The paper was published today in the Journal of the American Medical Association Network Open.

Diabetes Type 1 And Type 2 Adult Vaccination

Diabetes reduces the immune system's ability to fight certain infections. This raises the risk of dangerous diseases from vaccines to protect against-including flu, pneumonia, hepatitis B, tetanus and shingles.

People with diabetes may be at higher risk of getting certain diseases and also serious problems from diseases that could have been prevented with vaccines. Everyone should know what vaccines they need to protect themselves and discuss with their doctor if they are up to date with the vaccines.