Antibiotic resistance in bacteria is a growing global health crisis. Now, new research provides crucial details on bacterial defenses and how we could undermine them
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A new animal study published in The FASEB Journal reveals a significant link between HBV and the metabolic pathway of bile salts that could have implications for a new therapeutic strategy for HBV treatment
In Central America, Chagas disease, or American trypanosomiasis, is spread by the 'kissing bug' Triatoma dimidiata. By collecting DNA from the guts of these bugs, researchers reporting in PLOS Neglected Tropical Diseases have described patterns in the behavior of the bugs, the strain of parasite, and the communities of microbes that interact with the parasite.
The Walter Reed Army Institute of Research (WRAIR) administered the first vaccine in Phase 1 clinical trial to evaluate the safety and immunogenicity of a Marburg vaccine candidate in healthy adult volunteers.
By sequencing genetic material at a cell-by-cell level, researchers have described how type 2-high asthma affects the airways and results in mucus production with more detail than ever before. These findings , which help move forward scientific understanding of the biology behind asthma and could inform the development of targeted treatments for asthma and other airway diseases.
A new report from the Institute for Health Metrics and Evaluation (IHME) states that people born and living in Spain, Japan, and China are likely to live longer than those born and living in the United States.
Researchers have come up with self-lubricating condoms that become slippery or lubricated once they come in contact with skin. This would not only raise the pleasure factor of condom usage but also increase the use of condoms and reduce the incidence of sexually transmitted diseases (STDs) and unwanted pregnancies. This novel condom can stay lubricated for over 1,000 thrusts, say researchers. The study was funded by the Bill and Melinda Gates Foundation.
Biomedical engineers have demonstrated that, by injecting an artificial protein made from a solution of ordered and disordered segments, to solid scaffold forms in response to body heat, and in a few weeks seamlessly integrated into tissue.
The ability to combine these segments into proteins with unique properties will allow researchers to precisely control the properties of new biomaterials for applications in tissue engineering and regenerative medicine . The study was published in the journal Nature Materials.
A team led by Van Andel Research Institute (VARI) scientists have revealed the atomic-level structure of TRPM2, a protein that may be a promising drug target for conditions such as Alzheimer's disease and bipolar disorder. The study was published today in Nature
Letting women who've had a cesarean section and control pain medication through a catheter reduces their use of oral addictive opioid painkillers, report researchers. Their study included 576 women who had planned C-sections.
In such cases, it is common to inject a local anesthetic and a small dose of morphine into the spinal fluid. The morphine provides about 18 hours of pain relief after surgery, but significant pain may continue for several days.
In most cases, women are given oral opioids to manage that pain. Research presented at meetings is typically considered preliminary until published in a peer-reviewed journal.
Doping remains an ongoing problem in competitive sports , but have never before asked for athletes to rank the effectiveness of available anti-doping strategies. A new poll of a national pool of cyclists and field athletes finds that, according to the athletes, better diagnoses, increased bans and laws against doping are perceived to be more effective than increased goals or leniency programs.
From 2006 to 2015, there was a significant decrease in the intensive care unit (ICU) admissions among Medicare fee-for-service beneficiaries. The study was published online in the Annals of Internal Medicine .
Researchers used data from the Medicare Provider Analysis and Review file to assess hospitalizations involving acute and ICU care between 2006 and 2015 for Medicare fee-for-service beneficiaries (aged 65 years or older).