In an article published online October 12, 2018, by Leukemia, Medical University of South Carolina investigators report that a new compound enhances the efficacy of proteasome inhibitors (PIs), the standard-of-care for the treatment of multiple myeloma (MM), in cell culture and in preclinical models.
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More than one quarter (25.6%) of the authors writing clinical practice guidelines (CPGs) recommending high-priced medications failed to disclose relevant payments from drug companies, according to new research.
An increasing number of older adults are diagnosed with an end-stage liver disease. The end-stage liver disease is a life-threatening condition in which the liver stops working normally.
Measuring the percentage of weight regained following the maximum amount of weight loss after bariatric surgery can help predict a patient's risk of several serious health problems, according to a long-term, multicenter study led by University of Pittsburgh Graduate School of Public Health researchers.
ECFC, the leading nonprofit organization promoting choice in benefit solutions, applauds the proposed regulations from the U.S. Departments of the Treasury, Health and Human Services, and Labor regarding expanding the use of health reimbursement arrangements (HRAs) by employers.
Engineering Of A Polydisperse Small Heat-Shock Protein Reveals Conserved Motifs of Oligomer Plasticity
Small heat-shock proteins (sHSPs) are molecular chaperones that bind to unfolded proteins to prevent protein aggregation and defend against cellular stress. Mutations in human sHSPs are associated with inherited diseases including cataract and cardiomyopathy. The study was published in the journal Structure.
A new combination of two microscope technologies has provided scientists with a new insight into the biological processes occurring inside all living cells. This enables particles near the membrane of human cells, for example, to be better visualized. The study was published in the journal Nature Methods.
Women undergoing mastectomy for breast cancer experience improved postsurgical pain relief and reduced opioid when given to pectoralis nerve plane (PECS) block prior to surgery, suggests research presented at the ANESTHESIOLOGY ® 2018 annual meeting. The PECS block is a newer regional anesthesia technique that works by injecting long-acting anesthetics, guided by ultrasound, to numb the front of the chest wall before surgical incision.
Massage & Myotherapy Australia have today called upon all political parties contesting seats in the Victorian state election to answer to what the community and doctors are telling them about the needs of palliative care patients.
Mrs. Hughes, Massage & Myotherapy Australia CEO, said that in the absence of adequate policies and funding that recognize their role, many professional therapists are asked to provide their services for free. In the long-term this is untenable. Among the palliative care community, massage is well known for its benefits in improving the quality of life of patients.
Critically ill patients in intensive care units (ICUs), according to the National Institute on Aging, part of the National Institutes of Health. The multi-site team that conducted the trial found no evidence that treatment with antipsychotic medicines haloperidol or ziprasidone affected delirium, survival, length of ICU or hospital stay or safety.
The findings from the Modifying the Impact of ICU-Associated Neurological Dysfunction-USA (MIND-USA), the study was published in The New England Journal of Medicine.