All news from Bio-Physics

Single Plane Illumination Microscopy In Cell Biology

Visualizing cell behavior has been the goal of many techniques developed in the 20th and 21st century. Cells were initially visualized after removing from the organism after death. However, real-time visualization of cells through fluorescent labeling still proved difficult due to the degree of transparency required to see the fluorescence.

Similarly, imaging techniques have had problems with light scattering. Selective plane illumination microscopy (SPIM) or light-sheet microscopy differs offers high-resolution imaging at various cell depths in live tissues.

Potential Side Effects of General Anesthesia

The short-term effects of anesthesia are usually short-lived and manageable, but long-term neurological effects are a potential concern. Anesthetics , and in particular the inhaled ones used to put patients "under" for surgery, are considered one of the most important medical advances in history, the opening of the door for the entire modern field of surgery.

There are an estimated 46 million surgical procedures done each year in the US, and all anesthetics which make almost every one of these surgeries possible remain among the most toxic and poorly understood of all drugs.

Clinician Praised For Saving lives In Intensive care

Clinician praised for saving lives in intensive care through research. Thousands of patients in Intensive Care Units (ICUs) have benefited from the clinical trials led in New Zealand by Auckland City Hospital intensive care specialist and clinical researcher Dr. Colin McArthur.

For more than two decades, Dr. McArthur and his colleagues have questioned and tested treatment options available to critically-ill patients in the ICU, to reveal the safest, most effective ways to treat illnesses that pose a threat to life.

Space Travel Affects Brain

Spending long periods in space not only leads to muscle atrophy and reductions in bone density, but it also has lasting effects on the brain. However, little is known about how different tissues of the brain react to exposure to microgravity, and it remains unclear whether and to what extent the neuroanatomical changes so far observed persist following return to normal gravity.

The study was published in the  New England Journal of Medicinethey show that differential changes in the three main tissues of the brain remain detectable for at least half a year after the end of their last mission.

Different Types Of Neurofibroma For Modification

UT Southwestern researchers have made a major advance in uncovering the biology of how many thousands of disfiguring skin tumors occur in patients with a genetic disorder called neurofibromatosis type 1 (NF1).

This scientific advance could slow the development of these tumors. The study was published in the journal  Cancer Discovery.

Emergency departments in 'crisis' as mental health patients left waiting

The emergency worker remembers when the "young and proud" Aboriginal man in his 20s was brought into the emergency department by his father. He was agitated and upset, He said he wanted to kill himself but he would not engage with us any further."

The man was seen by the psychiatry team and admitted as an involuntary patient. There were no beds available, and I was to stay in the ED until one became available. On his second day in the ED, I managed to escape.

Cardiac Event Detects Patients & Plaques Vulnerable To Subsequent Coronary Events

Results from the Lipid-Rich Plaque (LRP) study demonstrate the correlation between the presence of non-flow-limiting, non-intervened upon, lipid-rich plaques detected by NIRS-IVUS imaging and the development of a major adverse cardiac event (MACE ) from a de novo culprit lesion at both the patient level (vulnerable patients) and segment level (vulnerable plaques) within 24 months post intravascular imaging.

To Avoid Sleep Deprivation

If your mental or physical health is suffering, a lack of sleep may be to blame. Sleep is considered both restorative and restorative, and a full night's sleep is essential to our overall health and well-being. But with the frenzied pace of work, social and family demands, many people find that they are not getting the proper rest they need on a nightly basis.

Hair Cell Regrowth Restore Lost Hearing

New research marks an important step toward what may become a new approach to restore hearing lossScientists have been able to record the sensory hair cells found in the cochlea-a part of the inner ear that converts sound vibrations into electrical signals and can be permanently lost due to age or noise damage.

An estimated 30 million Americans suffer from some degree of hearing loss and people have long accepted this as a fact of life for the aging population. But animals, including birds, frogs, and fish, can regenerate lost sensory hair cells. The research appears in the  European Journal of Neuroscience.

"It's funny, but mammals are the oddballs in the animal kingdom when it comes to cochlear regeneration," says study coauthor Jingyuan Zhang of the biology department at the University of Rochester. "We're the only vertebrates that can not do it."

Determinants Of Fasting Hyperglucagonemia In Patients With Type 2 Diabetes

A new study examined the relationship between fasting hyperglucagonemia-which can negatively affect glucose metabolism in patients with type 2 diabetes (T2D) -and several biochemical and glycemic factors in subjects with T2D or in a nondiabetic control group. The study results, which help to elucidate the mechanisms that underlie fasting hyperglucagonemia, are published in  Metabolic Syndrome and Related Disorders.

Family acceptance of LGBT identity linked to reduced stress

Researchers have determined that those who identify as LGBT and have come to their family carry fewer stress hormones than those who have not come out, which may ultimately benefit their health.

The recent study by Zoccola and coauthor Andrew Manigault, MS, the study was published in the October issue of  Psychosomatic Medicine, discusses how to be able to comfortably talk about your sexual identity with family members specifically, appears to be most linked to output of the stress hormone cortisol, a hormone that if too much is produced, it can damage an individual's health.