Limiting sedation levels for older adults undergoing hip fracture repair did not reduce the risk of postoperative delirium. However, a subgroup analysis found that lighter sedation reduced the risk of postoperative delirium among older adults in better overall health. The study was published in JAMA Surgery.
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Critically ill patients in intensive care units (ICUs), according to the National Institute on Aging, part of the National Institutes of Health. The multi-site team that conducted the trial found no evidence that treatment with antipsychotic medicines-haloperidol or ziprasidone-affected delirium, survival, length of ICU or hospital stay or safety.
The findings from the Modifying the Incidence of Delirium USA (MIND USA). The study was published in the New England Journal of Medicine.
Space Tango of Lexington today announced a research collaboration to study Parkinson's disease (PD) and primary progressive multiple sclerosis (PPMS) in microgravity in conjunction with National Stem Cell Foundation (NSCF), Summit for Stem Cell Foundation, and New York Stem Cell Foundation ( NYSCF) Research Institute.
For the first time, cells with PD and PPMS will be sent to the International Space Station (ISS) for a unique opportunity to observe cell-to-cell interactions in the neurodegenerative disease when the gravitational forces act on cells are removed.
Psoriasis appears to be significantly associated with inflammatory bowel disease (IBD). The study was published in JAMA Dermatology. Researchers assessed case-control, cross-sectional, or cohort studies that examined either the odds or risk for IBD in patients with psoriasis.
New research adds to a growing body of evidence suggesting that the expansion of Medicaid under the Affordable Care Act (ACA) helped low-income families rely less on emergency department visits for medical care.
The study abstract, "Effect of Affordable Care Act Medicaid Expansion on Emergency Department Visits by Uninsured Patients in Illinois 2009-2015," will be presented on Friday, Nov. 2, at the American Academy of Pediatrics (AAP) 2018 National Conference & Exhibition in Orlando, Fla.
Delayed care is a critically important factor in the survival of patients with head and neck cancer, and the patients who most often experience these delays are African American, according to two new studies at the Medical University of South Carolina (MUSC) and Hollings Cancer Center. The study was published in JAMA Otolaryngology-Head & Neck Surgery.
An international collaboration co-led by researchers at the Walter and Eliza Hall Institute has made a discovery that could make therapeutic insulins more effective by better mimicking the way insulin works in the body. The findings could improve treatments for diabetes, to that disease of the lives of millions of people worldwide.
The study was published in Nature Communications. The study reveals the first definitive 3-D image of how insulin successfully interacts with its receptor to 'gatekeeper' for transmitting information into cells in a process that is crucial for instructing cells to lower blood sugar levels in the body.
Understanding exactly what this process looks like could inform the design of faster-acting and longer-lasting insulin therapies.
Parents of vulnerable newborns in neonatal intensive care units (NICUs) who feel less resilient may experience more symptoms of psychological distress, including depression and anxiety. A snapshot from an ongoing cross-sectional study exploring this relationship was presented during the American Academy of Pediatrics (AAP) National Conference & Exhibition.
Preliminary findings suggest that these parents in interventions that bolster resilience, such as kangaroo care, may help them to better contend with psychological distress related to their child being in the NICU.
Inflammation, which is the root cause of autoimmune disorders including arthritis, Type 1 diabetes, irritable bowel syndrome, and Crohn's disease, has unexpected effects on body clock function and can lead to sleep and shiftwork-type disorders. The study was published in the journal Genes & Development.
If only we could regrow our broken bones like Harry Potter, Skele-gro style. Or, at the very least, heal up like a limb-regenerating newt. Alas, we humans possess no such abilities. Though our bodies cannot break bones, the older we get, the shoddier that patch job gets.
As for cartilage, the crucial cushioning that keeps our bones from rubbing together – once that's gone, it's gone for good. The study was published in Cell.
High blood levels of troponin, a protein released by injured heart muscle, can tell if someone recently experienced a heart attack. Measuring lower, but still problematic, levels of troponin can provide useful long-term information for cardiologists. The study was published in Annals of Internal Medicine.
A bucket containing a soupy green mixture sits under a table in Nduna Ewrong-Nxumalo's consultation room in downtown Johannesburg, South Africa's economic hub.