An investigational oral antibiotic called zoliflodacin was well-tolerated and successfully cured most cases of uncomplicated gonorrhea when tested in Phase 2 multicenter clinical trial, according to findings published in the New England Journal of Medicine. The National Institute of Allergy and Infectious Diseases (NIAID), part of the US National Institutes of Health, sponsored the clinical study.
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Even relatively short-term use of opioids can increase the risk of developing atrial fibrillation (AF) in patients in their mid 30s, new research suggests. A retrospective analysis of more than 850,000 veterans in the United States (mean age, 38 years) showed that 29% of the 3000 participants with AF had been prescribed an opioid, whereas only 15% of those without AF had.
Individuals with a body mass index (BMI) that falls above or below the healthy range of 21 to 25 kg/m² may be losing years off their life, research suggests. Specifically, a BMI of 30 kg/m2 or higher is linked to a 4-year reduction in lifespan compared with a healthy BMI range.
Fresh insights into how zebrafish repair their damaged nerve connections could aid the development of therapies for people with spinal cord injuries. Scientists have found the immune system plays a key role in helping zebrafish nerve cells to regenerate after injury.
The University of North Carolina Lineberger Comprehensive Cancer Center researchers have found that mailing self-collection kits to test for high-risk human papillomavirus infection has the potential to boost cervical cancer screening especially for low-income women who are overdue for testing.
Despite years of attention to the problem, U.S. hospitals have made little headway in preventing severe cases of bedsores among older Americans, a new study shows. Researchers found that across hospitals in three states, the rate of bedsores among Medicare patients dropped by 40% between 2009 and 2014.
Millions of people are living with the long-term consequences of cancer and its treatment, but currently, there is very little research on the problems they face and how these can be tackled, according to the UK's National Cancer Research Institute (NCRI).
A research team has identified a method to analyze biomolecules and their inhomogeneous charge distributions with carbon nanotube thin film transistors. Researchers have identified a technique to detect, measure and analyze biomolecules with complicated charge distributions. The study was published in the Journal of Applied Physics.
A recently developed technique known as light-sheet fluorescence microscopy has led to many biological discoveries by allowing researchers to create 3-D images of tissue, even live animal embryos, using fluorescent tags.
Now, researchers report the ability to increase the imaging depth of light-sheet fluorescence microscopy with the use of an optical phenomenon known as three-photon absorption. The study was published in the journal Optics Letters, the researchers report in detail how three-photon absorption can be used with light-sheet fluorescence microscopy to image deeper into tissues.