A new form of therapy may halt or even reverse a form of progressive vision loss that, until now, has inevitably led to blindness. This hyper-targeted approach offers hope to individuals living with spinocerebellar ataxia type 7 (SCA7) and validates a new form of therapy with the potential to treat neurogenetic diseases effectively and with far fewer side effects than other medications. Details of this therapy appear in the latest issue of Science Translational Medicine
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New research suggests that infant girls fed I am formulated are more likely to develop severe menstrual pain as young adults. The finding adds to the growing body of literature that suggests exposure to I am formulated during early life may have detrimental effects on the reproductive system. The study appears online in the journal Human Reproduction
Current standard imaging techniques for initial staging of prostate cancer often underestimate the extent of disease beyond the prostate. A study featured in The Journal of Nuclear Medicine 's November issue demonstrates that prostate-specific membrane antigen (PSMA) positron emission tomography / computed tomography (PET / CT) can pinpoint prostate cancer locations with superior accuracy
Artificial intelligence (AI) technology improves the ability of brain imaging to predict Alzheimer's disease, according to a study published in the journal Radiology
Breakthrough Mouse Model for Diabetic Kidney Disease Suggests a Role for Immune and Inflammatory Pathways
Scientists led by Duke-NUS Medical School have designed mice that successfully emulate a severe form of kidney damage in humans with diabetes, called diabetic nephropathy. Genetic analyzes of the mice led to the surprising finding that expression of genes controlling immune and inflammatory responses may play a causal role in promoting kidney damage, and suggest these pathways might be promising targets for therapy
Androgen deprivation therapy was associated with a 72 % higher risk of heart failure according to a study of patients with prostate cancer. In the Journal of Clinical Pharmacology study, incidence rates of heart failure per 100 person-years within a 1-year follow-up period were 4.00 and 1.89 for androgen deprivation therapy users and nonusers, respectively
Although the herbal supplement kratom is still legal and widely available, its opioid-like effects have caused significant withdrawal symptoms in at least two newborns in the United States and that should raise concerns, say
Adolescents with a particular variant of an opioid receptor have less response to a part of the prefrontal cortex that evaluates rewards, compared to those with the other version of the gene, say at Georgetown University Medical Center (GUMC)
The number of severe maternal morbidities (SMM) a pregnant woman has been linked to her risk of maternal death, according to a study by ICES and St. Michael's Hospital. SMM is defined by potentially life-threatening conditions such as ICU admission, invasive ventilation, and cardiac conditions that develop during pregnancy
Although Bangladesh attained remarkable success in curbing child mortality rate over the last 25 years, more than six hundred thousand are born prematurely each year in Bangladesh. Awareness about health and nutrition of mothers is important to decrease premature birth, discussants at a roundtable observed.
With the government's implementation of the Ayushman Bharat-National Health Protection Mission in September 2018, the health insurance sector in India stands to gain like never before. A health policy for the socio-economically underprivileged sections of the country, Ayushman Bharat will likely benefit nearly 500 million Indians or 100 million families, by providing them with health insurance of up to Rs 5 lakh per year. Although the underlying framework for the scheme's pricing and delivery is still under consideration, the central and state governments will finance it.
An international research team led by members of the University of Colorado School of Medicine faculty has identified a genetic connection between rheumatoid arthritis-associated interstitial lung disease and idiopathic pulmonary fibrosis. The findings are published in the current issue of the New England Journal of Medicine.