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Confidential Medical Services: Both Parents and Children Should Agree

When it comes to preventive care and confidential medical services, parents and their adolescent children actually agree with each other. They both believe that preventive care is important, that adolescents should be provided with opportunities to speak with their doctor, one-on-one, and that some services should be confidential. These findings are reported by University of Illinois at Chicago and their colleagues in the  Journal of Adolescent Health

Preclinical Studies: Synthetic DMAbs Protect Against Ebola

Scientists at The Wistar Institute and collaborators have successfully engineered novel DNA-encoded monoclonal antibodies (DMAbs) targeting Zaire Ebolavirus that were effective in preclinical models. Study results, published online in  Cell Reports, showed that DMAbs were expressed over a wide window of time and offered complete and long-term protection against lethal virus challenges.

DMAbs may also provide a novel powerful platform for rapid screening of monoclonal antibodies enhancing preclinical development. The Weiner Laboratory is also developing an anti-Ebola virus DNA vaccine. Preclinical results from this were published recently in the  Journal of Infectious Diseases .

Insights into How HIV Becomes Infectious

HIV, the virus that causes AIDS, has been studied extensively ever since the AIDS epidemic was officially recognized by health professionals in the early 1980s. During that time, research has led to the development of effective antiretroviral drugs that in many cases prevent an HIV-infected person from developing AIDS.

Influenza Virus can Evolve Resistance to Favipiravir, Study

The influenza virus can evolve resistance to an anti-flu drug currently in development for use in pandemics but only if there are multiple genetic mutations, a study has found. Scientists at Imperial College London, in collaboration with Public Health England, have discovered that two genetic mutations would be needed for the virus to develop resistance to favipiravir, an experimental antiviral developed in Japan.

Multiple Triggers for Kawasaki Disease

Researchers have evidence that Kawasaki Disease (KD) does not have a single cause. By studying weather patterns and geographic distributions of patients in San Diego, the research team determined that this disease has influenced multiple environmental triggers by a combination of temperature, precipitation and wind patterns.

Mechanism Used by Lung Cancer Cells to Obtain Glucose Identified

Scientists at the UCLA Jonsson Comprehensive Cancer Center have identified sodium glucose transporter 2, or SGLT2, as a mechanism that lung cancer cells use to obtain glucose, which is key to their survival and promotes tumor growth. The finding provides evidence that SGLT2 may be a novel biomarker that scientists can use to help diagnose precancerous lung lesions and early-stage lung cancers.

Investigating Foodborne Disease Outbreak Based on Simulation Game

How do you prepare for a crisis? When does the general public have to be notified of a risk? And how should authorities deal with scientific uncertainty? These questions are being discussed by food safety experts from Germany and Bosnia-Herzegovina in Sarajevo from 22- 26 October 2018 at the practice workshop "Dealing with foodborne disease outbreaks".