All news from Geriatrics

Organ-on-Chip Research Accelerated by New European Society Launching, Finding

The new European Organ-on-Chip Society (EUROoCS) was officially launched at the third International Organ-on-Chip Symposium, held on 8 and 9 November 2018 at the University of Technology in Eindhoven, the Netherlands.

The Society will encourage development and coordination of Organ-on-Chip research in Europe in support of better health for all. Membership will be open from 2019 to all researchers in the field, providing access benefits to the pending digital Organ-on-Chip platform, the annual meeting and the future society journal.

A Low-Gluten, High-Fiber Diet Healthier

When healthy people eat a low-gluten and fibre-rich diet compared with a high-gluten diet, they experience less intestinal discomfort including less bloating. Researchers at University of Copenhagen show that this is due to changes of the composition and function of gut bacteria.

Role of Proteins to Break up Energy Structures in Oxygen Starved Heart Cells

Researchers found that the filamin A-Drp1 complex mediates mitochondrial fission in a mouse model of hypoxic heart cells. Results show that hypoxic stress brought about the interaction of filamin A with Drp1 and increased Drp1 activity in heart cells. This process led to mitochondrial fragmentation and cell senescence. Further investigation demonstrated that the drug cilnidipine suppressed Drp1-filamin A complex formation and preserved heart cell function.

Rise in Mortality Risks with Social Isolation, Study

A large study links social isolation with a higher risk of death from all causes combined and heart disease for all races studied, and with increased cancer mortality in white men and women. The study, appearing in the  American Journal of Epidemiology, says addressing social isolation holds promise if studies show interventions are effective, as they could be relatively simple and could influence other risk factors, as social isolation is also associated with hypertension, inflammation, physical inactivity, smoking, and other health risks.