Researchers recommend greater action to promote best practice as a new study reveals a rise in prescriptions of opioids for treating chronic pain rise between 1998 and 2018. A review of opioid prescribing in the UK has shown that UK doctors are prescribing more and stronger opioid drugs to patients.
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Women with early breast cancer who received once-weekly, hypofractionated radiotherapy exhibited low rates of normal tissue effects comparable to those of conventional radiation therapy at 10 years, according to study findings presented at American Society for Radiation Oncology Annual Meeting.
The burden of liver disease continues to increase in the UK, with liver cirrhosis reported to be the third most common cause of premature death. Iron overload, a condition that impacts liver health, was traditionally associated with genetic disorders such as hereditary haemochromatosis, however, it is now increasingly associated with obesity, type-2 diabetes and non-alcoholic fatty liver disease.
A novel cytotoxic diterpenoid, chabrolin A (1) (possessing an unprecedented terpenoid skeleton), as well as three new cytotoxic sesquiterpenoids, parathyrsoidins E–G (2–4), were isolated by cytotoxicity-guided fractionation from soft corals Nephthea chabroli and Paralemnalia thyrsoides. The structures of the new compounds were determined by extensive analysis of spectroscopic data.
Scientists at McMaster University have discovered several new biomarkers from a single drop of blood that could allow earlier and more definitive detection of cystic fibrosis (CF), a genetic disease which strikes both children and adults, causing chronic problems with the digestive system and the lungs.
Thrombosis is a harmful activation of the clotting process that prevents bleeding in healthy people. Thrombosis is associated with the occurrence of strokes, ischemic heart disease, and other blood vessel-related diseases.
St. Jude Children's Research Hospital scientists have discovered a subset of helper T cells that may help to redefine understanding and treatment of chronic, debilitating inflammatory disorders. The research appears today as an advance online publication in the journal Nature.
Patients treated with chemotherapy for a solid tumor are at much higher risk than was previously thought of developing a highly lethal blood cancer as a result of that treatment.
A policy designed to reduce hospital readmissions through financial penalties was associated with a significant increase in post-discharge mortality for patients with heart failure and pneumonia, according to a large-scale study by researchers in Beth Israel Deaconess Medical Center's (BIDMC) Smith Center for Outcomes Research in Cardiology.
Only one in four U.S. seniors with chronic health problems prepare documents detailing their treatment preferences ahead of undergoing risky surgery, a study suggests. The 393 patients in the study, all 65 or older, had multiple illnesses and underwent high-risk surgery, either planned or as an emergency.
Patients who undergo heart surgery do not experience major memory changes either better or worse when compared with those who have a much less invasive, catheter-based procedure, according to a study published online today in the Annals of Thoracic Surgery.
Legacy prescribing of certain drugs, such as antidepressants and proton pump inhibitors (PPIs), is common, according to a study published in the November/December issue of the Annals of Family Medicine.