All news from Nephrology

New Method for Studying Gene Expression Could Improve Understanding of Brain Disease

It takes a lot of cells to make a human brain. The organ houses not only an enormous quantity of neurons but also an impressive diversity of neuron types. In recent years, scientists have been developing inventories of these cell classes-information that will be essential for understanding how the brain works. Contributing to this effort, a new study from Rockefeller scientists describe a novel methodology for characterizing neurons and their gene expression patterns with unmatched precision

Mechanism for Cracking Biochemical Code Uncovered

Since the time of ancient Egypt, humans have been making and breaking secret codes to retain and gain critical information. Human life itself is based upon a genetic code of DNA or RNA sequences which cells read and translate into proteins—the building blocks of life.

Recent scientific discoveries have revealed the body's mechanisms for transcribing DNA regulated by the "histone code"—different chemical marks on the tails of histone proteins, which are macromolecules within cell nuclei responsible for packaging and structuring DNA.

Astronaut Health: ISS Microbes Should be Monitored to Avoid Threat

Scientists have identified strains of the bacterium Enterobacter on the International Space Station (ISS), which they say should be studied for potential health implications for astronauts on future missions. Researchers at NASA’s Jet Propulsion Laboratory (JPL) and California Institute of Technology in the US investigated five strains of Enterobacter that were isolated from the space toilet and the exercise platform on the ISS in March 2015.

Dengue fever in Bangladesh, Rise in the Cases in Dhaka

Dengue season usually begins with June’s monsoon rains in Dhaka. An unavoidable fact of life, it proves deadly to a handful of unfortunate victims but by September it has mostly disappeared from the Bangladeshi capital.

But this year the disease has seen more than a tripling of numbers of recorded cases in the city – alongside a lengthening of its season. And the explosion is being reported in other countries too. Dengue, a mosquito-borne viral disease, has been spreading rapidly in the past few years.

Optogenetics: Insights into Structure Changes in Tissues

In optogenetics, researchers use light to control protein activity. This technique allows them to alter the shape of embryonic tissue and to inhibit the development of abnormalities. Now, scientists in EMBL's De Renzis group have enhanced the technique to stop organ-shaping processes in fruit fly embryos. Their results, published in the EMBO Journal, allow control over a crucial step in embryonic development.

Resistant Gonorrhea: Promising New Treatment Approaches

Edward W. Hook III, MD, Endowed Professor of Infectious Disease Translational Research, departments of medicine, epidemiology and microbiology, at the University of Alabama-Birmingham, believes the drug zoliflodacin “is the most promising new antimicrobial for gonorrhea treatment we have had in nearly 20 years.”