All news from Anaesthesiology

Complex Genetic Interactions Identified by Rank Order

Applying new math, Kristina Crona, an American University assistant professor who researches in the area of mathematical biology, and her colleagues show how ranking pathogen mutants can help scientists understand how mutants evolve to resist drug treatments. This line of research could have implications for the treatment of diseases that can resist drug treatments, such as HIV and malaria.

Association between ‘Thorase’ Activity and schizophrenia

Researchers at Johns Hopkins Medicine report they have identified rare genetic variations in a protein called Thorase, which is responsible for breaking down receptors at the connections between neurons in the brain. By targeting Thorase's function, the scientists say they have successfully reversed anti-social behavior in mice genetically modified to carry the variants by using the anti-epilepsy drug perampanel.

Combination therapy to treat PCOS and Severe Hirsutism

Combining an estrogen-progesterone oral contraceptive pill (OCP) with the anti-androgen bicalutamide is more effective than an OC alone in treating severe hirsutism in women with polycystic ovary syndrome (PCOS), according to a double-blind randomized controlled trial from Italy.

A Novel Therapy to Prevent Dangerous Results of Snakebites

A University of Arizona researcher developing a therapy to prevent or delay the dangerous results of rattlesnake and other venomous snakebites in humans has shown that a combination of carbon monoxide and iron inhibits snake venom's effects for up to an hour in animals, a major advance in bringing the treatment to market.