A new study published in the Journal of Biological Chemistry has shown that the enzyme that makes the El Tor family of Vibrio cholerae resistant to those antibiotics has a different mechanism of action from any comparable proteins observed in bacteria so far. Understanding that mechanism better equips researchers to overcome the challenge it presents in a world with increasing antibiotic resistance.
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Exposure to the children's television series Peppa Pig may be contributing to unrealistic expectations of primary care and encouraging inappropriate use of services suggests a doctor in the Christmas issue of The BMJ.
Benzodiazepine and related drug use is associated to a 40% increase in mortality among persons with Alzheimer's disease , according to a study from the University of Eastern Finland. The study findings were published in the International Journal of Geriatric Psychiatry .
Applying new math, Kristina Crona, an American University assistant professor who researches in the area of mathematical biology, and her colleagues show how ranking pathogen mutants can help scientists understand how mutants evolve to resist drug treatments. This line of research could have implications for the treatment of diseases that can resist drug treatments, such as HIV and malaria.
A ground-breaking new research hub has been set up to help halt future outbreaks of killer diseases like Ebola and Zika. The landmark project will help to increase vaccine coverage across the globe and improve the response to deadly outbreaks through the rapid deployment of life-saving vaccines.
Community screening for osteoporosis could prevent more than a quarter of hip fractures in older women, according to a study published in the journal The Lancet. The study has shown that a simple questionnaire, combined with bone mineral density measurements for some, would help identify those at risk of hip fracture.
Researchers at Johns Hopkins Medicine report they have identified rare genetic variations in a protein called Thorase, which is responsible for breaking down receptors at the connections between neurons in the brain. By targeting Thorase's function, the scientists say they have successfully reversed anti-social behavior in mice genetically modified to carry the variants by using the anti-epilepsy drug perampanel.
Expressing concern over rising number of abortion-related deaths in the country, a parliamentary committee on women's healthcare policies has recommended amendment in Medical Termination of Pregnancy Act to help remove the weak spots in existing norms.
Combining an estrogen-progesterone oral contraceptive pill (OCP) with the anti-androgen bicalutamide is more effective than an OC alone in treating severe hirsutism in women with polycystic ovary syndrome (PCOS), according to a double-blind randomized controlled trial from Italy.
A University of Arizona researcher developing a therapy to prevent or delay the dangerous results of rattlesnake and other venomous snakebites in humans has shown that a combination of carbon monoxide and iron inhibits snake venom's effects for up to an hour in animals, a major advance in bringing the treatment to market.
The American Academy of Pediatrics (AAP) favors public cord blood banks and emphasizes the importance of parental education in its new policy statement on cord blood banking for potential future transplantation. The study is published in online in Pediatrics.
In new research published in the journal Cell, researchers have found that ignored pieces of DNA play a critical role in the development of immune cells (T cells). These areas activate a change in the structure of DNA that brings together crucial elements necessary for T cell formation. The big bang discovery might support in combating diseases.