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Intravescical Prostatic Protrusion: Predictor of Alpha Blockers Response

The researchers investigate the efficacy of tamsulosin in patients with lower urinary tract symptoms (LUTS) and benign prostatic enlargement (BPE) with an intravescical prostatic protrusion (IPP). Ultrasound measurement of the IPP has been previously described as an effective instrument for the evaluation of benign prostatic obstruction (BPO) and could help in clarifying the role of alpha-blockers in patients with (BPE).

Prevalence in Severe Psychological Trauma in 0.5% of the Population

Post-traumatic stress disorder (PTSD) can sometimes occur in a particularly severe form, known as complex post-traumatic stress disorder. In both forms of PTSD, patients suffer from an over-activation of the memories of traumatic events — in the form of images, smells, and sounds. In complex PTSD, patients also undergo personality changes and have difficulties with interpersonal relationships, in particular suffering from deep-seated mistrust, incapacity for intimacy, and greatly impaired self-worth.

COPD Patients on Long-term ICS Exposure are at Risk of Bone Fractures

In the present large cohort of patients newly treated for COPD, long-term ICS use at high doses was associated with a modest but significant increase in the risk of fractures of the hip and upper extremity. Long-term ICS use did not result in a higher risk of nonvertebral fractures in postmenopausal women, compared with men, with COPD. Clinicians need to carefully consider the benefits and risks of prescribing ICSs to patients with COPD, particularly over the longer term, and the prescribed dose should be kept as low as possible.