All news from Epidemiology

Role of Enzyme OGG1 in Treatment of Inflammatory Diseases

An enzyme that normally repairs damaged DNA, may be the key to a new treatment for inflammatory diseases. Inflammatory diseases such as COPD and septicemia (blood poisoning) represent a growing threat to public health. Such conditions are commonly the result of an overactive immune system.

found that a protein in the cell membranes of sperm plays a keyrole in how they find their way to eggs. The PMCA protein may also help explain how egg cells only interact with sperm from the same species. PMCA may even be a target of drug discovery.

Read more: https://phys.org/news/2018-11-unraveling-mystery-sperm-cells.html#jCp

Researchers have found that a protein in the cell membranes of sperm plays a keyrole in how they find their way to eggs. The PMCA protein may also help explain how egg cells only interact with sperm from the same species. PMCA may even be a target of drug discovery.

Read more at: https://phys.org/news/2018-11-unraveling-mystery-sperm-cells.html#jCp

Evolution of Vertebrates: Genomic Keys Uncovered

The vertebrates, the animal group to which humans belong, are extremely diverse and have colonized virtually all of the planet's ecosystems. For many years there was some debate as to which changes in our ancestors' genome could have contributed to the successful evolution of the vertebrates.

Now, an international team of scientists co-led by Spanish researchers from the Center for Genomic Regulation (CRG), the Spanish National Research Council (CSIC), and the National Center for Scientific Research (CNRS) in France, has just described the processes that ultimately helped to yield the diversity of gene functions and regulation during the transition from invertebrates to vertebrates.

Medical Targets Might be Achieved by Battling Social Factors

Engulfed in social stigma and discrimination, HIV / AIDS is an issue of society still addresses in hushed voices despite the progression we claim to have achieved globally. In honor of World AIDS Day 2018 (Celebrated on December 1) the National STD / AIDS Control Program (NSACP) has partnered up with its stakeholders, NGO partners and the private sector to approach this disease with open hearts and minds.

Antibiotics’ Judicious Use: ICMR Releases Guidelines

Irrational prescription of broad-spectrum antibiotics, poor regulations around sale of antibiotics are some of the key factors driving AMR in our country. To ensure judicious use of antibiotics in healthcare facilities, the Indian Council of Medical Research (ICMR) released on November 20, Antimicrobial Stewardship Guidelines to advise hospitals in setting up Antimicrobial Stewardship Programmes (AMSP) for the purpose.

Swarmlike Collective Behavior in Bicycling, Insights

Nature is full of examples of large-scale collective behavior; humans also exhibit this behavior, most notably in pelotons, the mass of riders in bicycle races. Using aerial video footage of bicycle races, analyzed peloton motion to determine what causes changes in the group's large-scale collective behavior and found that riders move through the peloton in a similar manner to circulation in a fluid.